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NeuroMab™ Anti-SEZ6 Antibody, Clone NR30P
A functional antibody raised against Human, Mouse, Rat, Cynomolgus Monkey SEZ6.
- Host Species:
- Mouse
- Species Reactivity:
- Human; Mouse; Rat; Cynomolgus Monkey
- Applications:
- FC; IHC; In Vitro; In Vivo
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
inquiryDescription
Species Reactivity
Clonality
Host Species
Clone Number
Applications
Relevant Diseases
Formulation
Preservatives
Concentration
Purification
Purity
Endotoxin Level
Low Endotoxin < 1 EU/mg
Shipping
Storage
Research Use Only
Figure 1 shows SEZ6 expression in HEK-293T cells modified to overexpress human SEZ6 protein (h293T-HuSEZ6) using the anti-SEZ6 antibody SC17.33.
Axis corresponds to concentration of 3E antibody (Fab) and Y axis corresponds to NGF binding (percentage of maximal UR). Increasing concentrations of Fab E3 blocked the interaction of NGF with p75 and trkA, as indicated by a decrease in signal (measured in UR). When the concentration of E3 antibody (Fab) was equal to that of NGF, no NGF binding was observed (indicated by zero signal).
![](https://img.creative-biolabs.com/neuros/productImages/NRP-0523-P437-1.png)
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