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Creative Biolabs

HOT NeuroMab™ Anti-Tau Antibody(NRP-0422-P1760)

[CAT#: NRP-0422-P1760] Review(5) Q&As(3)

Functional antibody against Human Tau

Host Species:
Mouse; Humanized
Species Reactivity:
Human
Applications:
ELISA; In Vitro; In Vivo

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Product Overview

Description

This antibody is specific for conformation dependent epitope. The reactivity depends on both the N terminus (amino acids 7–9), and an amino acid sequence of tau (amino acids 313–322) in the third microtubule binding domain. It can also recognize aggregated tau, and efficiently reduces pathological tau species.

Species Reactivity

Human

Clonality

Monoclonal

Host Species

Mouse; Humanized

Isotype

IgG1

Applications

ELISA; In Vitro; In Vivo

Relevant Diseases

Alzheimer's Disease
Product Properties

Formulation

PBS only

Preservatives

BSA Free

Concentration

1mg/mL

Purification

Purified recombinant IgG prepared by affinity chromatography on Protein A from a mammalian cell line

Purity

> 95% (SDS-PAGE)

Endotoxin Level

Regular Endotoxin < 5 EU/mg
Low Endotoxin < 1 EU/mg

Shipping

Gel Packs

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Research Use Only

For research use only
Target

Target

Tau

Official Name

Tau

Full Name

Tau

Alternative Names

CD14

Gene ID

4137(Human); 17762(Mouse); 29477(Rat)

Uniprot ID

P10636(Human); P10637(Mouse); P19332(Rat)
Publications

Publications (0)

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Customer Reviews and Q&As
Customer Reviews Average Customer Ratings Overall
5.0
user
Excellent
The results are consistent, and the antibody's performance is reliable
I highly recommend the anti-Tau antibody, clone MC-1 for any research involving tau proteins. It has shown excellent specificity and sensitivity in our immunofluorescence assays, allowing us to distinguish between different forms of tau in various stages of neurodegeneration.
user
Excellent
Produce more precise and detailed results
Its high specificity for pathological tau has made it essential for our Western blot and immunofluorescence applications. The quality of our results has significantly improved since incorporating this antibody.
user
Excellent
This antibody has exceeded our expectations in every aspect
We used it in our studies on Tau-related neurodegeneration and found it to be highly specific with minimal non-specific binding. It works well in both fixed tissue samples and live cell imaging. The data we obtained using MC-1 has been crucial in our publications.
user
Excellent
It is a product we trust for accurate results
The MC-1 antibody has performed exceptionally well in our immunoprecipitation experiments. Its ability to selectively bind Tau has allowed us to isolate and study various Tau isoforms. The quality and performance of this antibody have greatly enhanced our research capabilities.
user
Excellent
An excellent reagent
Its high specificity and sensitivity have allowed us to detect even minor changes in Tau protein levels. It has a high affinity for its target and produces clear, reproducible results. It's become a staple in our lab's toolbox.
Q&As
Is this antibody suitable for use in human samples?
Yes, the antibody is suitable for use in human samples for research purposes, allowing researchers to investigate tau aggregates in human tissues and cells.
What type of cells can this antibody be used on?
The antibody can be used on a variety of cell types, including neuronal cells, making it versatile for different research projects.
How long is the shelf life of this antibody?
This antibody has a shelf life of 1 year when stored properly, ensuring researchers can use it for multiple experiments over time.
For Research Use Only. Not For Clinical Use.
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