- Host Species:
- Mouse
- Species Reactivity:
- Human; Mouse
- Applications:
- WB; IP; ELISA; IHC; Block; In Vitro; In Vivo
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
inquiryProduct Overview
Description
Brain uptake of therapeutic antibodies is severely limited by their size. To achieve enhanced BBB crossing, Creative Biolabs developed a BBB shuttle antibody platform by utilizing the endogenous macromolecule transportation pathway, known as receptor-mediated transcytosis (RMT). The engineered antibody-based carrier is believed to significantly to increase the macromolecule brain entry to combat CNS diseases.
Notes: The BBB antibody is made-to order and available in a customized format. Please don't hesitate contact us for more details.
Notes: The BBB antibody is made-to order and available in a customized format. Please don't hesitate contact us for more details.
Species Reactivity
Human; Mouse
Clonality
Monoclonal
Host Species
Mouse
Applications
WB; IP; ELISA; IHC; Block; In Vitro; In Vivo
Relevant Diseases
Alzheimer's Disease
Product Properties
Storage
Store at -20°C. Do not aliquot the antibody.
Research Use Only
For research use only
Target
Target
Tau
Official Name
MAPT
Full Name
Tau Protein
Alternative Names
MAPT; DDPAC; FTDP-17; MAPTL; MSTD; MTBT1; MTBT2; PPND; PPP1R103; TAU; microtubule associated protein tau; Tau proteins; tau-40
Publications
Publications (0)
Neural Antibodies
Neural Genes
Kits
Neural Cell Lines
Scientific Resources
Customer Reviews and Q&As
Customer Reviews
Average Customer Ratings
Overall
5.0
ExcellentHighly recommend for any lab focused on neurobiologyThe antibody's ability to cross the blood-brain barrier has significantly enhanced our in vivo studies, providing more accurate and reliable data. The results are consistent and reproducible, which is critical for our research.
ExcellentIt’s reliable and worth every pennyWe've been using this antibody for our ELISA assays to quantify tau levels in cerebrospinal fluid samples. The sensitivity and specificity are exceptional, allowing us to detect even the smallest changes in tau concentrations.
ExcellentWe've been using this antibody in vitro to study tau aggregationThe antibody has shown excellent performance in detecting tau aggregates with high specificity. The detailed protocols provided by the company have been incredibly helpful. It's a high-quality product that we trust for our experiments.
ExcellentIt’s an excellent product that has greatly facilitated our researchThe antibody's ability to cross the blood-brain barrier and target tau proteins with high specificity has provided us with clear and detailed images. It's a valuable tool for understanding the distribution and pathology of tau in the brain.
Q&As
What is the recommended concentration and application protocol for using the antibody in western blotting?
For western blotting, we recommend using the anti-Tau BBB shuttle antibody at a concentration of 1:1000 to 1:5000. Optimal results are achieved with standard protein extraction and blotting protocols, ensuring sensitive and specific detection of tau protein bands.
What are the advantages of using the BBB shuttle antibody compared to other anti-tau antibodies on the market?
Our antibody offers superior blood-brain barrier penetration properties, allowing for efficient brain tissue labeling without the need for additional permeabilization steps. This feature simplifies experimental workflows and enhances the accuracy of tau protein detection in complex biological samples.
For Research Use Only. Not For Clinical Use.
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