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Creative Biolabs

NeuroMab™ Anti-Tau BBB Shuttle Antibody(NRZP-1022-ZP2790)

[CAT#: NRZP-1022-ZP2790] Review(4) Q&As(2)

Host Species:
Mouse
Species Reactivity:
Human; Mouse
Applications:
WB; IP; ELISA; IHC; Block; In Vitro; In Vivo

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Product Overview

Description

Brain uptake of therapeutic antibodies is severely limited by their size. To achieve enhanced BBB crossing, Creative Biolabs developed a BBB shuttle antibody platform by utilizing the endogenous macromolecule transportation pathway, known as receptor-mediated transcytosis (RMT). The engineered antibody-based carrier is believed to significantly to increase the macromolecule brain entry to combat CNS diseases.
Notes: The BBB antibody is made-to order and available in a customized format. Please don't hesitate contact us for more details.

Species Reactivity

Human; Mouse

Clonality

Monoclonal

Host Species

Mouse

Applications

WB; IP; ELISA; IHC; Block; In Vitro; In Vivo

Relevant Diseases

Alzheimer's Disease
Product Properties

Storage

Store at -20°C. Do not aliquot the antibody.

Research Use Only

For research use only
Target

Target

Tau

Official Name

MAPT

Full Name

Tau Protein

Alternative Names

MAPT; DDPAC; FTDP-17; MAPTL; MSTD; MTBT1; MTBT2; PPND; PPP1R103; TAU; microtubule associated protein tau; Tau proteins; tau-40
Publications

Publications (0)

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Customer Reviews and Q&As
Customer Reviews Average Customer Ratings Overall
5.0
user
Excellent
Highly recommend for any lab focused on neurobiology
The antibody's ability to cross the blood-brain barrier has significantly enhanced our in vivo studies, providing more accurate and reliable data. The results are consistent and reproducible, which is critical for our research.
user
Excellent
It’s reliable and worth every penny
We've been using this antibody for our ELISA assays to quantify tau levels in cerebrospinal fluid samples. The sensitivity and specificity are exceptional, allowing us to detect even the smallest changes in tau concentrations.
user
Excellent
We've been using this antibody in vitro to study tau aggregation
The antibody has shown excellent performance in detecting tau aggregates with high specificity. The detailed protocols provided by the company have been incredibly helpful. It's a high-quality product that we trust for our experiments.
user
Excellent
It’s an excellent product that has greatly facilitated our research
The antibody's ability to cross the blood-brain barrier and target tau proteins with high specificity has provided us with clear and detailed images. It's a valuable tool for understanding the distribution and pathology of tau in the brain.
Q&As
What is the recommended concentration and application protocol for using the antibody in western blotting?
For western blotting, we recommend using the anti-Tau BBB shuttle antibody at a concentration of 1:1000 to 1:5000. Optimal results are achieved with standard protein extraction and blotting protocols, ensuring sensitive and specific detection of tau protein bands.
What are the advantages of using the BBB shuttle antibody compared to other anti-tau antibodies on the market?
Our antibody offers superior blood-brain barrier penetration properties, allowing for efficient brain tissue labeling without the need for additional permeabilization steps. This feature simplifies experimental workflows and enhances the accuracy of tau protein detection in complex biological samples.
For Research Use Only. Not For Clinical Use.
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