NeuroMab™ Anti-Tau BBB Shuttle Antibody (NRZP-1022-ZP3114)
- Host Species:
- Humanized
- Species Reactivity:
- Human; Mouse
- Applications:
- IHC; ELISA; In Vitro
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Notes: The BBB antibody is made-to order and available in a customized format. Please don't hesitate contact us for more details.
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Figure 1: Chimeric and murine DC8E8 and Tau 151-391/4R combinations
Figure 2: Humanized and chimeric DC8E8 and Tau 151-391/4R combinations. Antibodies co-expressing assembly-encoded DC8E8 RHA or DC8E8 RHB co-expressed with DC8E8 RKA or DC8E8 RKB were compared to antibody binding of fully aptamer antibodies.
Figure 3: Combination of humanized and chimeric DC8E8 and Tau 151-391/4R: the Vk version is (the light is installed on the Chain together with what is).
Figure 4 Immunohistochemical staining of Alzheimer's disease brain tissue with humanized DC8E8 antibody (IgG1).
Figure 5 Immunohistochemical staining of FTDP-17 brain (mutated in R406W Tau) using humanized DC8E8 antibody (IgG1).
Figure 6 Immunohistochemical staining for corticobasal degeneration using humanized DC8E8 antibody (IgG1).
Figure 7 Immunohistochemical staining of stein-leventhal syndrome using humanized DC8E8 antibody (IgG4).
Figure 8 Heat resistance of the candidate derivatized DC8E8 antibody: the purified antibody was heated at the commanded Clock temperature for 10 points, then cooled to 4°C, and then Tau combined ELISA was performed.
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