NeuroMab™ Anti-Tau40 Antibody(NRP-0422-P1674)
[CAT#: NRP-0422-P1674]
Functional antibody against Human Tau40
- Host Species:
- Chimeric
- Species Reactivity:
- Human
- Applications:
- WB; ELISA; In Vitro; In Vivo
Certificate of Analysis Lookup
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
inquiryProduct Overview
Species Reactivity
Human
Clonality
Monoclonal
Host Species
Chimeric
Applications
WB; ELISA; In Vitro; In Vivo
Relevant Diseases
Alzheimer's Disease
Product Properties
Formulation
PBS only
Preservatives
BSA Free
Concentration
1mg/mL
Purification
Purified recombinant IgG prepared by affinity chromatography on Protein A from a mammalian cell line
Purity
> 95% (SDS-PAGE)
Endotoxin Level
Regular Endotoxin < 5 EU/mg
Low Endotoxin < 1 EU/mg
Low Endotoxin < 1 EU/mg
Shipping
Gel Packs
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Research Use Only
For research use only
Target
Product Pictures
ELISA
Figure 1 ELISA measuring ch17C1, ch17C1(N31Q) mIgG2a and ch17C1(N31Q) mIgG1 in the combination of Agly and recombinant Tau.
ELISA
Figure 2 ELISA measurements of ch17C1(N31Q) mIgG2a and ch17C1(N31Q, I48V).
FuncS
Figure 3 Pathological aggregation of Tau protein in vivo and in brains of AD and tauopathies transgenic mice.
FuncS
Figure 4 shows TauP301L treated with ch17C1(N31Q) and ch4E4(N30Q), Western blotting to detect soluble and insoluble human tau in mice.
FuncS
Figure 5 application ch17C1 (N31Q) and ch4E4 (N30Q) 24 hours after the last administration of peritoneal animal mean plasma drug concentration. Mean plasma drug concentrations of ch17C1 (N31Q) and ch4E4 (N30Q) were 145 and 200 μg/mL, respectively.
FuncS
Figure 6 TauP301L mice processed by double-exam Y-maze with ch17C1 (N31Q) and ch4E4 (N30Q) spatial working memory impairments assessed.
Publications
Publications (0)
Neural Antibodies
For Research Use Only. Not For Clinical Use.
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