NeuroMab™ Anti-TDP43 BBB Shuttle Antibody(NRZP-1022-ZP2628)
- Host Species:
- Mouse
- Species Reactivity:
- Human
- Applications:
- ELISA; IHC; ICC; Inhib; In Vitro; In Vivo
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Notes: The BBB antibody is made-to order and available in a customized format. Please don't hesitate contact us for more details.
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Fig.1 showing that 3F1 1 mouse monoclonal antibody to disease- associated N-terminal TDP43 epitope does not react with physiologic stress granules.
Immunofluorescent staining of human TDP-43 and TDP-43 oligomers in the brain slices of wild type and 6- and 12-month-old TDP-43 Tg+/+ transgenic mice. Cells with anti-TDP oligomer staining, TDP-43 staining, and DAPI staining are shown (scale bar, 100 μιη). Blocked area was presented at higher magnification in the last column (scale bar, 25 μιη).
Fig.2 shows antibody blocking of misfolded TDP-43 transmission in HEK293 cells.
Immunofluorescent staining of human TDP-43 and TDP-43 oligomers in the brain slices of wild type and 6- and 12-month-old TDP-43 Tg+/+ transgenic mice. Cells with anti-TDP oligomer staining, TDP-43 staining, and DAPI staining are shown (scale bar, 100 μιη). Blocked area was presented at higher magnification in the last column (scale bar, 25 μιη).
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