Human Anti-ITGAM Monoclonal Antibody (CBP1527)

Product Overview

Description

CaMKII is composed of multiple isoforms, which are derived from four closely related gene products. Alpha, beta, gamma and delta have different but overlapping expression patterns.
Human anti-CaMK II inhibitor alpha antibody detects mouse calcium/calmodulin-dependent protein kinase II alpha (CaMK II alpha), which is activated by calcium ions (Ca2 +) and Ca2 +/calmodulin complex (CaM) The serine/threonine kinase. CaMK II is expressed in glutamatergic excitatory neurons and constitutes the main postsynaptic density protein. It is very important for the regulation of synaptic transmission, and may play a role in learning and memory.

Immunogen

Peptide sequence C-DEKLSPYGDGGDVGQI that corresponds to amino acids 10-25 of mouse calcium/calmodulin-dependent protein kinase II inhibitor 1 (CaMK II N alpha).

Species Reactivity

Mouse; Rat

Clonality

Monoclonal

Host Species

Human

Isotype

HuCAL Fab bivalent

Clone Number

CBP1527

Applications

IHC-Fr

Research Areas

Growth and Development

Conjugation

Unconjugated

Product Properties

Form

Liquid

Formulation

PBS
0.01% Thiomersal

Concentration

0.5 mg/ml

Purification

Metal chelate affinity chromatography.

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store at +4°C or at -20°C if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted.
Avoid repeated freezing and thawing as this may denature the antibody.
Should this product contain a precipitate we recommend micr°Centrifugation before use.

Target

CD11b

Official Name

ITGAM

Full Name

Integrin alpha M

Alternative Names

ITGAM; CD11B; CR3A; MAC-1; MAC1A; MO1A; SLEB6; integrin subunit alpha M

Gene ID

3684 (Human); 16409 (Mouse); 25021 (Rat)

Uniprot ID

P11215 (Human); P05555 (Mouse)

References

1. Radwańska, K. et al (2010) Differential regulation of CaMKII inhibitor beta protein expression after exposure to a novel context and during contextual fear memory formation.

Publications