Rat Anti-MBP Monoclonal Antibody (CBP1568)

Product Overview

Description

The rat anti-MBP antibody recognizes myelin basic protein (MBP), a component of myelin that is thought to play a role in the formation of nerve myelin in the central nervous system.

Immunogen

Bovine myelin basic protein.

Species Reactivity

Bovine; Human

Clonality

Monoclonal

Host Species

Rat

Isotype

IgG2b

Clone Number

CBP1568

Applications

ELISA; IF; IHC-Fr

Research Areas

Growth and Development

Conjugation

Unconjugated

Product Properties

Form

Tissue Culture Supernatant-liquid

Formulation

Tissue Culture Supernatant-liquid
0.09% Sodium Azide

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store at +4°C or at -20°C if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted.
Avoid repeated freezing and thawing as this may denature the antibody.
Should this product contain a precipitate we recommend micr°Centrifugation before use.

Target

Myelin Basic Protein

Official Name

MBP

Full Name

Myelin basic protein

Alternative Names

MBP; entrez:4155; myelin basic protein; Myelin basic protein; Myelin_BP; IPR000548

Gene ID

4155(Human); 17196(Mouse); 24547(Rat)

Uniprot ID

P02686(Human); P04370(Mouse); P02688(Rat)

References

1. Glynn, P. et al. (1987) Basic protein dissociating from myelin membranes at physiological ionic strength and pH is cleaved into three major fragments.
2. Groome, N. et al. (1988) New monoclonal antibodies reactive with defined sequential epitopes in human myelin basic protein.
3. Matsuo, A. et al. (1997) Unmasking of an unusual myelin basic protein epitope during the process of myelin degeneration in humans: a potential mechanism for the generation of autoantigens.
4. Jackson, S.J. et al. (2004) Cannabinoid-mediated neuroprotection following interferon-gamma treatment in a three-dimensional mouse brain aggregate cell culture.
5. Friess, M. et al. (2016) Intracellular ion signaling influences myelin basic protein synthesis in oligodendrocyte precursor cells.

Publications