Mouse Anti-GFAP Monoclonal Antibody (CBP2182)
[CAT#: NAB201034LS]
Anti-GFAP Monoclonal Antibody
- Host Species:
- Mouse
- Species Reactivity:
- Human; Mouse
- Applications:
- WB
Certificate of Analysis Lookup
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
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Description
GFAP is an intermediate filament protein coexpressed with vimentin in mature astrocytes. Intermediate filaments (IFs), together with microtubules and microfilaments, form an interconnected network of the cytoskeleton, which gives cells their form, shape and functions. This gene encodes one of the major intermediate filament proteins of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. The appearance of GFAP breakdown products in serum and CSF have been linked to traumatic brain injury (TBI).
Immunogen
Recombinant human GFAP protein
Species Reactivity
Human; Mouse
Clonality
Monoclonal
Host Species
Mouse
Isotype
IgG1
Clone Number
CBP2182
Applications
WB
Application Notes
WB (0.05-1.0 µg/mL)
Relevant Diseases
Brain Tumors; Alzheimer's Disease; Parkinson's Disease; Neurocutaneous Syndromes
Research Areas
Neuroinflammation
Conjugation
Unconjugated
Product Properties
Form
Liquid
Formulation
PBS, pH 7.2, containing 0.09% sodium azide.
Concentration
0.5 mg/mL
Purification
Affinity chromatography
Purity
>95%, as determined by Coomassie stained SDS-PAGE.
Shipping
The product is shipped at 4°C. Upon receipt, store it immediately at the recommended temperature.
Storage
Store at -20°C. Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody.
Handling Advice
Store at -20°C. Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody.
Research Use Only
For research use only, not for diagnostic or therapeutic use.
Target
References
1. Khakh BS, et al. 2015. Nat Neurosci. 18(7): 942.
2. Brenner M. 2014. Neurosci Lett. 565:7-13.
3. Hol EM, et al. 2015. Curr Opin Cell Biol. 32:121.
2. Brenner M. 2014. Neurosci Lett. 565:7-13.
3. Hol EM, et al. 2015. Curr Opin Cell Biol. 32:121.
Publications
Publications (0)
Kits
Neural Antibodies
Neural Genes
For Research Use Only. Not For Clinical Use.
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