Product Overview

Immunogen

Partial human cathepsin D recombinant protein (21-412 a.a.) expressed in 293E cells.

Species Reactivity

Human

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG1, κ

Clone Number

CBP2190

Applications

Relevant Diseases

Brain Tumors; Alzheimer's Disease; Parkinson's Disease; Neurocutaneous Syndromes

Research Areas

Neuroinflammation

Conjugation

Unconjugated

Product Properties

Form

Liquid

Formulation

PBS, pH 7.2, containing 0.09% sodium azide.

Concentration

0.5 mg/mL

Purification

Affinity chromatography

Purity

>95%, as determined by Coomassie stained SDS-PAGE.

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the recommended temperature.

Storage

Store at -20°C. Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody.

Handling Advice

Store at -20°C. Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody.

Research Use Only

For research use only, not for diagnostic or therapeutic use.

Target

Cathepsin D

Official Name

CTSD

Full Name

Cathepsin D

Alternative Names

CTSD; CLN10; CPSD; HEL-S-130P; cathepsin D

Gene ID

1509 (Human); 13033 (Mouse)

Uniprot ID

P07339 (Human); P18242 (Mouse)

References

1. Vetvicka V, et al. 1994. Cancer Lett. 79:131.
2. Johansson AC, et al. 2003. Cell Death Differ. 10:1253.
3. Cavailles V, et al. 1988. Nucleic Acids Res. 16:1903.
4. Bidere N, et al. 2003. J. Biol. Chem. 278:31401.
5. Conus S, et al. 2012. J. Biol. Chem. 25:21142.
6. Koike M, et al. 2001. J. Neurosci. 21:7526.
7. Cullen V, et al. 2009. Mol. Brain 2:5.
8. Dian D, et al. 2014. Histol. Histopathol. 29:433.

Publications