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Creative Biolabs

Mouse Anti-CKMT1B Monoclonal Antibody (CBP2479)

[CAT#: NAB2010600LS]

Anti CKMT1 Monoclonal Antibody

Host Species:
Mouse
Species Reactivity:
Human; Rat
Applications:
WB; IHC-P; ICC

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Product Overview

Description

CKMT1 is the mitochondrial specific creatine kinase subunit that is ubiquitously expressed in mammals. CKMT1 is mainly localized to the mitochondrial intermembrane space and plays an important role in cellular energetics. Impairment in CKMT1 due to oxidative and radical-induced damage has been reported in numerous diseases including neurodegenerative disorders. Overexpression of CKMT1 is observed in several tumors in which high energy consumption is required for proliferation.

Species Reactivity

Human; Rat

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG1, κ

Clone Number

CBP2479

Applications

WB; IHC-P; ICC

Application Notes

WB (0.5 -10 µg/mL); IHC-P (2.0-10 µg/mL); ICC (2.0-10 µg/mL)

Relevant Diseases

Brain Tumors; Alzheimer's Disease; Parkinson's Disease; Neurocutaneous Syndromes

Research Areas

Neuroinflammation

Conjugation

Unconjugated
Product Properties

Form

Liquid

Formulation

PBS, pH 7.2, containing 0.09% sodium azide.

Concentration

0.5 mg/mL

Purification

Affinity chromatography

Purity

>95%, as determined by Coomassie stained SDS-PAGE.

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the recommended temperature.

Storage

The antibody solution should be stored undiluted between 2°C and 8°C.

Handling Advice

Upon receipt, the antibody solution should be stored undiluted at -20°C, and protected from prolonged exposure to light.

Research Use Only

For research use only, not for diagnostic or therapeutic use.
Target

Target

CKMT1B

Official Name

CKMT1B

Full Name

Creatine kinase, mitochondrial 1B

Alternative Names

CKMT1B; CKMT; CKMT1; UMTCK; creatine kinase; mitochondrial 1B

Gene ID

1159 (Human); 12716 (Mouse)

Uniprot ID

P12532 (Human); P30275 (Mouse)
Protocols

Protocols

Its related pathways are Viral mRNA Translation and Regulation of activated PAK-2p34 by proteasome mediated degradation.
Publications

Publications (0)

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For Research Use Only. Not For Clinical Use.
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