Mouse Anti-BRAP Monoclonal Antibody (CBP2483)

[CAT#: NAB2010604LS]

Anti BRAP Monoclonal Antibody

Host Species:: Mouse

Species Reactivity:: Human; Rat

Applications:: WB; IHC-P

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Product Overview

Description

BRCA1 associated protein (BRAP) is a cytosolic protein that negatively regulates MAP kinase activation by inhibiting the formation of the Raf/MEK complex. BRAP also inhibits nuclear translocation and promotes the retention of several proteins, including BRCA1, in the cytoplasm by binding to their nuclear localization signal sequence.

Immunogen

Purified recombinant human BRAP protein fragments expressed in E. coli

Species Reactivity

Human; Rat

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG1, κ

Clone Number

CBP2483

Applications

WB; IHC-P

Application Notes

WB (0.5-2 µg/mL); IHC-P (2.0-10 µg/mL)

Relevant Diseases

Brain Tumors; Alzheimer's Disease; Parkinson's Disease; Neurocutaneous Syndromes

Research Areas

Neuroinflammation

Conjugation

Unconjugated

Product Properties

Form

Liquid

Formulation

PBS, pH 7.2, containing 0.09% sodium azide.

Concentration

0.5 mg/mL

Purification

Affinity chromatography

Purity

>95%, as determined by Coomassie stained SDS-PAGE.

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the recommended temperature.

Storage

The antibody solution should be stored undiluted between 2°C and 8°C.

Handling Advice

Upon receipt, the antibody solution should be stored undiluted at -20°C, and protected from prolonged exposure to light.

Research Use Only

For research use only, not for diagnostic or therapeutic use.

Target

BRAP

Official Name

BRAP

Full Name

BRAP

References

1. Modell SM, et al. 2014. J Relig Health. 53(3):715.
2. Castro E & Eeles R. 2012. Asian J Androl. 14(3):409.
3. Pristauz G, et al. 2010. Wien Med Wochenschr. 160(7-8):158.

Publications