Mouse Anti-TH Monoclonal Antibody (CBP2749)

Product Overview

Description

TH(Tyrosine 3-monooxygenase) converts L-tyrosine to L-3,4-dihydroxyphenylalanine (L-DOPA), the essential and rate-limiting step to formation of DA and other catecholamines. TH plays an important role in the physiology of adrenergic neurons and can be used as a marker for DA and noradrenergic neurons.

Expression Host

Mammalian cells

Immunogen

TH fusion protein Ag23075

Species Reactivity

Human

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG1

Clone Number

CBP2749

Applications

IF; WB; ELISA

Application Notes

IF : 1:20-1:200; WB : 1:500-1:1000

Research Areas

Neural Signal Transduction

Conjugation

Unconjugated

Product Properties

Form

Liquid

Formulation

PBS, 0.1% sodium azide and 50% glycerol pH 7.3.

Preservatives

Yes

Concentration

1000 μg/ml

Purification

Antigen affinity purification

Purity

>95%, as determined by SDS-PAGE

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store at -20°C. Stable for one year after shipment.

Research Use Only

For research use only, not for diagnostic or therapeutic use.

Target

Tyrosine Hydroxylase

Official Name

Full Name

Tyrosine hydroxylase

Alternative Names

Dystonia 14;
DYT14;
DYT5b;
EC 1.14.16.2;
OTTHUMP00000011225;
OTTHUMP00000011226;
ple;
Protein Pale;
TH;

Gene ID

7054(Human); 21823(Mouse); 25085(Rat)

Uniprot ID

P07101(Human); P24529(Mouse); P04177(Rat)

References

1. Deng, J., Zhou, X., Wang, M., Wang, M., Zhou, L., Meng, G.,... & Yu, L. (2019). The effects of interleukin 17A on left stellate ganglion remodeling are mediated by neuroimmune communication in normal structural hearts. International journal of cardiology, 279, 64-71. 2. Xia, Y., Zhang, G., Han, C., Ma, K., Guo, X., Wan, F.,... & Xiong, N. (2019). Microglia as modulators of exosomal alpha-synuclein transmission. Cell Death & Disease, 10(3), 1-15. 3. Zheng, C., Chen, G., Tan, Y., Zeng, W., Peng, Q., Wang, J.,... & Zhang, Z. (2018). TRH analog, taltirelin protects dopaminergic neurons from neurotoxicity of MPTP and rotenone. Frontiers in Cellular Neuroscience, 12, 485.

Publications