Mouse Anti-SOX2 Monoclonal Antibody (CBP2764)

Product Overview

Description

SRY (sex determining region Y)-box 2 is a transcription factor involved in neural stem cell maintenance and has been used in somatic cell reprogramming.

Expression Host

Mammalian cells

Immunogen

SOX2 fusion protein Ag13635

Species Reactivity

Human; Porcine; Mouse

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG1

Clone Number

CBP2764

Applications

IF; IHC; WB; ELISA

Application Notes

IF : 1:20-1:200; IHC : 1:20-1:200; WB : 1:500-1:1000

Research Areas

Neural Signal Transduction

Conjugation

Unconjugated

Product Properties

Form

Liquid

Formulation

PBS, 0.1% sodium azide and 50% glycerol pH 7.3.

Preservatives

Yes

Concentration

1000 μg/ml

Purification

Antigen affinity purification

Purity

>95%, as determined by SDS-PAGE

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store at -20°C. Stable for one year after shipment.

Research Use Only

For research use only, not for diagnostic or therapeutic use.

Target

SOX2

Official Name

SOX2

Full Name

SRY (sex determining region Y)-box 2

Alternative Names

ANOP3; MCOPS3; SOX2; Transcription factor SOX 2

Gene ID

6657(Human); 20674(Mouse)

Uniprot ID

P48431(Human); P48432(Mouse)

References

1. He, J., Shi, J., Zhang, K., Xue, J., Li, J., Yang, J.,... & Liu, X. (2017). Sox2 inhibits Wnt-β-catenin signaling and metastatic potency of cisplatin-resistant lung adenocarcinoma cells. Molecular Medicine Reports, 15(4), 1693-1701. 2. Xu, X., Zhang, X., Wei, C., Zheng, D., Lu, X., Yang, Y.,... & Wang, Y. (2020). Targeting SLC7A11 specifically suppresses the progression of colorectal cancer stem cells via inducing ferroptosis. European Journal of Pharmaceutical Sciences, 152, 105450.

Publications