Mouse Anti-SOD2 Monoclonal Antibody (CBP2782)

Product Overview

Description

SOD2 (superoxide dismutase 2, mitochondrial) is restricted to the perinuclear area in a cell with aggregate formation of mutant SOD1(PMID:12659845). It functions as the first line of antioxidant defense against highly reactive superoxide radicals and it appears to be early predictors for survival in septic patients with with MIF(PMID:20863520).

Expression Host

Mammalian cells

Immunogen

SOD2 fusion protein Ag21388

Species Reactivity

Human; Mouse; Rat; Porcine

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG1

Clone Number

CBP2782

Applications

IHC; WB; ELISA

Application Notes

IHC : 1:20-1:200; WB : 1:500-1:1000

Research Areas

Neuron

Conjugation

Unconjugated

Product Properties

Form

Liquid

Formulation

PBS, 0.1% sodium azide and 50% glycerol pH 7.3.

Preservatives

Yes

Concentration

1000 μg/ml

Purification

Antigen affinity purification

Purity

>95%, as determined by SDS-PAGE

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store at -20°C. Stable for one year after shipment.

Research Use Only

For research use only, not for diagnostic or therapeutic use.

Target

SOD2

Official Name

SOD2

Full Name

Superoxide dismutase 2, mitochondrial

Alternative Names

Indophenoloxidase B;
IPO B;
IPOB;
Manganese containing superoxide dismutase;
Manganese SOD;
Manganese superoxide dismutase;
Mangano superoxide dismutase;
Mn SOD;
Mn superoxide dismutase;
MNSOD;

Gene ID

6648(Human); 20656(Mouse); 24787(Rat)

Uniprot ID

P04179(Human); P09671(Mouse); P07895(Rat)

References

1. Wu, X., Dai, H., Liu, L., Xu, C., Yin, Y., Yi, J.,... & Li, S. (2019). Citrate reduced oxidative damage in stem cells by regulating cellular redox signaling pathways and represent a potential treatment for oxidative stress-induced diseases. Redox biology, 21, 101057. 2. Zhu, S., Li, W., Yang, X., Yu, W., Rao, T., Ruan, Y.,... & Li, C. (2018). Effects of autophagy on the spermatogonia of chronic hypoxic mice. American Journal of Translational Research, 10(12), 4119. 3. Wang, R., Dong, Z., Lan, X., Liao, Z., & Chen, M. (2019). Sweroside alleviated LPS-induced inflammation via SIRT1 mediating NF-κB and FOXO1 signaling pathways in RAW264. 7 cells. Molecules, 24(5), 872.

Publications