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Creative Biolabs
Product

Mouse Anti-MAPT Monoclonal Antibody (CBP2789)

[CAT#: NAB20101866CR]

Mouse Monoclonal (1E9A8) to MAPT

Host Species:
Mouse
Species Reactivity:
Human; Mouse; Rat; Porcine
Applications:
IHC; WB; ELISA

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Product Overview

Description

The microtubule-associated protein TAU (MAPT or TAU) is encoded by MAPT gene, which locates on human chromosome 17q21, binds to the tubulin subunit of microtubule and promotes its assembly and stability. Most TAU is expressed in neurons, and TAU isoform is expressed in the peripheral nervous system while the others are expressed in the central nervous system. TAU links axonal microtubules with C-terminus to neural plasma membrane components with its N-terminus, suggesting the participation in intracellular signal transduction and neuron's development and viability.

Expression Host

Mammalian cells

Immunogen

TAU fusion protein Ag21926

Species Reactivity

Human; Mouse; Rat; Porcine

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG2c

Clone Number

CBP2789

Applications

IHC; WB; ELISA

Application Notes

IHC : 1:20-1:200; WB : 1:500-1:1000

Research Areas

Neural Signal Transduction

Conjugation

Unconjugated
Product Properties

Form

Liquid

Formulation

PBS, 0.1% sodium azide and 50% glycerol pH 7.3.

Preservatives

Yes

Concentration

1000 μg/ml

Purification

Antigen affinity purification

Purity

>95%, as determined by SDS-PAGE

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store at -20°C. Stable for one year after shipment.

Research Use Only

For research use only, not for diagnostic or therapeutic use.
Target

Target

Tau

Official Name

MAPT

Full Name

Microtubule-associated protein tau

Alternative Names

MAPT; Neurofibrillary tangle protein; Paired helical filament tau; PHF tau; Phospho-TAU (Thr181); pThr181 Tau; TAU

Gene ID

4137(Human); 17762(Mouse); 29477(Rat)

Uniprot ID

P10636(Human); P10637(Mouse)
Publications

Publications (0)

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