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Creative Biolabs

Mouse Anti-MFN1 Monoclonal Antibody (CBP2848)

[CAT#: NAB20101925CR]

Mouse Monoclonal (3F11C11) to MFN1

Host Species:
Mouse
Species Reactivity:
Human
Applications:
IF; IHC; WB; ELISA

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Product Overview

Description

Mitofusin-1 (MFN1) is a mediator of mitochondrial fusion. This protein and mitofusin 2 are homologs of the Drosophila protein fuzzy onion (Fzo). Mitofusins are large predicted GTPases located in outer mitochondrial membrane. They are essential for outer membrane fusion by interacting with each other to facilitate mitochondrial targeting. The mitofusins are the first known protein mediator of mitochondrial fusion, and mediate developmentally regulated post-meiotic fusion of mitochondria.Mfn1 is required on adjacent mitochondria to mediate fusion via interactions of a heptad repeat region that mediates oligomerization of the protein.

Expression Host

Mammalian cells

Immunogen

MFN1 fusion protein Ag4890

Species Reactivity

Human

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG2a

Clone Number

CBP2848

Applications

IF; IHC; WB; ELISA

Application Notes

IF : 1:20-1:200; IHC : 1:20-1:200; WB : 1:500-1:1000

Research Areas

Metabolism

Conjugation

Unconjugated
Product Properties

Form

Liquid

Formulation

PBS, 0.1% sodium azide and 50% glycerol pH 7.3.

Preservatives

Yes

Concentration

1000 μg/ml

Purification

Antigen affinity purification

Purity

>95%, as determined by SDS-PAGE

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store at -20°C. Stable for one year after shipment.

Research Use Only

For research use only, not for diagnostic or therapeutic use.
Target

Target

Mitofusin 1

Official Name

MFN1

Full Name

Mitofusin 1

Alternative Names

DKFZp762F247; FLJ20693; Fzo homolog; hfzo1; hfzo2; MFN1; mitofusin 1; Transmembrane GTPase MFN1

Gene ID

55669(Human)

Uniprot ID

Q8IWA4(Human)
Publications

Publications (0)

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