Product Overview

Description

CHAT (choline acetyltransferase) belongs to the carnitine/choline acetyltransferase family. It catalyzes the reversible synthesis of acetylcholine (ACh) from acetyl CoA and choline at cholinergic synapses. Defects in CHAT are the cause of congenital myasthenic syndrome with episodic apnea (CMSEA). CHAT is known to to be present exclusively in the cytoplasm of cholinergic neurons and anti-CHAT antibody has been considered as the best marker for cholinergic neurons.

Expression Host

Mammalian cells

Immunogen

CHAT fusion protein Ag19602

Species Reactivity

Human; Mouse; Rat

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG2b

Clone Number

CBP2853

Applications

WB; ELISA

Application Notes

WB : 1:500-1:1000

Research Areas

Neurotransmission

Conjugation

Unconjugated

Product Properties

Form

Liquid

Formulation

PBS, 0.1% sodium azide and 50% glycerol pH 7.3.

Preservatives

Yes

Concentration

1000 μg/ml

Purification

Antigen affinity purification

Purity

>95%, as determined by SDS-PAGE

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store at -20°C. Stable for one year after shipment.

Research Use Only

For research use only, not for diagnostic or therapeutic use.

Target

Choline Acetyltransferase

Official Name

CHAT

Full Name

Choline acetyltransferase

Alternative Names

Acetyl CoA choline O acetyltransferase;
Acetyl CoA:choline O acetyltransferase;
ChAT;
CHOACTase;
Choline acetylase;
choline acetyltransferase;
Choline O acetyltransferase;
Choline O-acetyltransferase;