Product
Anti-Rab8 Monoclonal Antibody (CBP3736)
[CAT#: NAB201299LS]
Anti-Rab8 Monoclonal Antibody [Biotin]
- Host Species:
- Mouse
- Species Reactivity:
- Human; Rat
- Applications:
- ICC
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
inquiryProduct Overview
Description
Rab8 is a small GTP/GDP binding protein that belongs to the RAS superfamily. Rab8 is an important participant of macroautophagy, and is essential for several apical transport pathways. Recruitment of Rab8a and TBK1 by the autophagy receptor optineurin initiates the autophagy process at specific protein aggregate site, which leads to the clearance of aggregated protein.
Immunogen
Recombinant human Rab8A
Species Reactivity
Human; Rat
Clonality
Monoclonal
Host Species
Mouse
Isotype
IgG2b, κ
Clone Number
CBP3736
Applications
ICC
Application Notes
ICC (0.2-5.0 µg/mL)
Relevant Diseases
Brain Tumors; Alzheimer's Disease; Parkinson's Disease; Neurocutaneous Syndromes
Research Areas
Neuroinflammation; Neurodegeneration
Conjugation
Alexa Fluor 594; Alexa Fluor 488; Alexa Fluor 498; Alexa Fluor 647; Alexa Fluor 700; APC; APC/Cyanine 7; APC/Fire 750; Biotin; Brilliant Violet 421; Brilliant Violet 510; Brilliant Violet 570; Brilliant Violet 570; Brilliant Violet 605; Brilliant Violet 650; Brilliant Violet 711; Brilliant Violet 750; Brilliant Violet 785; FITC; HRP; PE; Pacific Blue; PE/Cyanine 5; PE/Cyanine 7; PerCP; Spark YG 570
Product Properties
Form
Liquid
Formulation
PBS, pH 7.2, containing 0.09% sodium azide.
Concentration
0.5 mg/mL
Purification
Affinity Chromatography
Purity
>95%, as determined by Coomassie stained SDS-PAGE.
Shipping
The product is shipped at 4°C. Upon receipt, store it immediately at the recommended temperature.
Storage
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Research Use Only
For research use only, not for diagnostic or therapeutic use.
Target
References
1. Zhang X and Gao N. 2016. Small GTPases. 7:59
2. Just WW and Peränen J. 2016. Biochim Biophys Acta. 1863:1006
3. Ao X, et al. 2014. Cell Death Differ. 21(3):348
4. Corbier C and Sellier C. 2017. Small GTPases. 8:181
2. Just WW and Peränen J. 2016. Biochim Biophys Acta. 1863:1006
3. Ao X, et al. 2014. Cell Death Differ. 21(3):348
4. Corbier C and Sellier C. 2017. Small GTPases. 8:181
Publications
Publications (0)
Neural Antibodies
For Research Use Only. Not For Clinical Use.
