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Creative Biolabs

Anti-CD31 Monoclonal Antibody (CBP3741)

[CAT#: NAB2012112LS]

Anti-CD31 Monoclonal Antibody

Host Species:
Mouse
Species Reactivity:
Human; African green monkey; Baboon; Cynomolgus; Rhesus
Applications:
FC; ELISA; ICC; IHC

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Product Overview

Description

CD31 is a 130-140 kD type I transmembrane glycoprotein also known as platelet endothelial cell adhesion molecule-1 (PECAM-1) or Endocam. It is expressed on monocytes, platelets, granulocytes, endothelial cells and lymphocyte subsets. CD31 has been reported to bind CD38 and be involved in wound healing, angiogenesis, and cellular migration in an inflammatory situation.

Species Reactivity

Human; African green monkey; Baboon; Cynomolgus; Rhesus

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG1, κ

Clone Number

CBP3741

Applications

FC; ELISA; ICC; IHC

Application Notes

FCM (≤ 1.0 µg per million cells in 100 µL); ELISA (1.0 µg/mL); IHC (2.5-10 μg/mL)

Relevant Diseases

Brain Tumors; Alzheimer's Disease; Parkinson's Disease; Neurocutaneous Syndromes

Research Areas

Neuroinflammation; Neurodegeneration

Conjugation

Unconjugated
Product Properties

Form

Liquid

Formulation

PBS, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA.

Concentration

Batch Dependent

Purification

Affinity Chromatography

Purity

>95%, as determined by Coomassie stained SDS-PAGE.

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the recommended temperature.

Storage

Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody.

Research Use Only

For research use only, not for diagnostic or therapeutic use.
Target

Target

PECAM1

Official Name

PECAM1

Full Name

Platelet endothelial cell adhesion molecule

Alternative Names

PECAM1; CD31; CD31/EndoCAM; GPIIA'; PECA1; PECAM-1; endoCAM; platelet and endothelial cell adhesion molecule 1; PCAM-1

Gene ID

5175 (Human); 18613 (Mouse)

Uniprot ID

P16284 (Human); Q08481 (Mouse)
References

1. DeLisser H, et al. 1994. Immunol. Today 15:490.
2. Newman P, 1997. J. Clin. Invest. 99:3.
3. Fawcett J, et al. 1995. J. Cell Biol. 128:1229.
Publications

Publications (0)

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