Rat Anti-Human FGF-3 Monoclonal Antibody (CBP3750)

[CAT#: NAB2012136LS]

Anti-FGF-3 Monoclonal Antibody

Host Species:: Rat

Species Reactivity:: Human

Applications:: WB

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Product Overview

Description

FGF-3 is a member of the fibroblast growth factor family. FGF-3 is also associated with tumor metastasis and recurrence in human hepatocellular carcinoma. Like many other FGF proteins, FGF-3 plays an important role in embryonic development.

Immunogen

Human FGF-3 recombinant protein (28-212 a.a.) expressed in E.coli.

Species Reactivity

Human

Clonality

Monoclonal

Host Species

Rat

Isotype

IgG2a, κ

Clone Number

CBP3750

Applications

Application Notes

WB (0.5-2.0 µg/mL)

Relevant Diseases

Brain Tumors; Alzheimer's Disease; Parkinson's Disease; Neurocutaneous Syndromes

Research Areas

Neuroinflammation; Neurodegeneration

Conjugation

Unconjugated

Product Properties

Form

Liquid

Formulation

PBS, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA.

Concentration

Batch Dependent

Purification

Affinity Chromatography

Purity

>95%, as determined by Coomassie stained SDS-PAGE.

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the recommended temperature.

Storage

Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody.

Research Use Only

For research use only, not for diagnostic or therapeutic use.

Target

FGF-3

Official Name

FGF3

Full Name

INT-2 proto-oncogene protein

Alternative Names

FGF3; HBGF-3; INT2; fibroblast growth factor 3

References

1. Kiefer P, et al. 1991. Mol. Cell Biol. 11:5929.
2. Brookes S, et al. 1989. Oncogene 4:429.
3. Zelarayan LC, et al. 2007. Dev. Biol. 308:379.
4. Fekete DM. 2000. Trends Neurosci. 23:332.
5. Leger S, Brand M. 2002. Mech. Dev. 119:91.
6. Weisinger K, et al. 2012. Biol. Open 1:67.
7. Hatch EP, et al. 2007. Development 134:3615.
8. Antoine M, et al. 2005. Biochem. Biophys. Res. Commun. 338:1248.
9. Frenz DA, et al. 2010. Am. J. Med. Genet. A. 152A:2947.

Publications