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Creative Biolabs

Mouse Anti-Human CD286 Monoclonal Antibody (CBP3779)

[CAT#: NAB2012198LS]

Anti-CD286 Monoclonal Antibody

Host Species:
Mouse
Species Reactivity:
Human
Applications:
FC

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Product Overview

Description

Toll-like receptor 6 (TLR6), known as CD286, is one of the important receptors. TLR6 is colocalized with TLR2 on the cell surface of monocytes/macrophages, dendritic cells, granulocytes. The TLR2/TLR6 complex plays a role in the innate immune response to diacylated lipoprotein and peptidoglycan antigens.

Immunogen

Human TLR6 transfected Ba/F3 cells

Species Reactivity

Human

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG1, κ

Clone Number

CBP3779

Applications

FC

Application Notes

FCM (≤ 2.0 µg per 106 cells in 100 µL volume)

Relevant Diseases

Brain Tumors; Alzheimer's Disease; Parkinson's Disease; Neurocutaneous Syndromes

Research Areas

Neuroinflammation; Neurodegeneration

Conjugation

Unconjugated
Product Properties

Form

Liquid

Formulation

PBS, pH 7.2, containing 0.09% sodium azide.

Concentration

Batch Dependent

Purification

Affinity Chromatography

Purity

>95%, as determined by Coomassie stained SDS-PAGE.

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the recommended temperature.

Storage

Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody.

Research Use Only

For research use only, not for diagnostic or therapeutic use.
Target

Target

CD286

Official Name

TLR6

Full Name

Toll-like receptor 6

Alternative Names

TLR6
References

1. Takeuchi O, et al. 2001. Int. Immunol. 13:933
2. Shimizu T, et al. 2005. J. Immunol. 175:4641
3. Into T, et al. 2004. Cell Microbiol. 6:187
Publications

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