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Mouse Anti-Rat CD106 Monoclonal Antibody (CBP3819)

[CAT#: NAB2012316LS]

Anti-CD106 Monoclonal Antibody

Host Species:
Mouse
Species Reactivity:
Rat
Applications:
FC; IHC-F

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Product Overview

Description

CD106 is a 110 kD transmembrane protein also known as VCAM-1 and INCAM-110. It is an immunoglobulin superfamily member and is expressed on bone marrow stromal cells, myeloid cells, splenic dendritic cells and endothelial cells (activated by cytokines). CD106 is a counter-receptor for VLA-4 (α4β1 integrin) and LPAM-1 (α4β7 integrin). The interactions of CD106 and VLA-4 or LPAM-1 play an important role in binding of leukocytes to activated endothelial cells and leukocyte extravasation at inflammatory sites.

Immunogen

Rat VCAM-1 transfected L5178Y cells

Species Reactivity

Rat

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG1, κ

Clone Number

CBP3819

Applications

FC; IHC-F

Application Notes

FCM (≤ 1.0 µg per million cells in 100 µL volume)

Relevant Diseases

Brain Tumors; Alzheimer's Disease; Parkinson's Disease; Neurocutaneous Syndromes

Research Areas

Neuroinflammation; Neurodegeneration

Conjugation

Unconjugated
Product Properties

Form

Liquid

Formulation

PBS, pH 7.2, containing 0.09% sodium azide.

Concentration

1.0 mg/mL

Purification

Affinity Chromatography

Purity

>95%, as determined by Coomassie stained SDS-PAGE.

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the recommended temperature.

Storage

Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody.

Research Use Only

For research use only, not for diagnostic or therapeutic use.
Target

Target

VCAM1

Official Name

VCAM1

Full Name

Vascular Cell Adhesion Molecule 1

Alternative Names

Vascular Cell Adhesion Molecule 1; CD106 Antigen; INCAM-100; Vascular Cell Adhesion Protein 1; V-CAM 1; VCAM-1; CD106;

Gene ID

7412(Human); 22329(Mouse); 25361(Rat)

Uniprot ID

P19320(Human); P29533(Mouse); P29534(Rat)
Publications

Publications (0)

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For Research Use Only. Not For Clinical Use.
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