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Creative Biolabs
Product

Mouse Anti-Rat Synaptotagmin-6 Monoclonal Antibody (CBP3827)

[CAT#: NAB2012331LS]

Anti-Synaptotagmin-6 Monoclonal Antibody

Host Species:
Mouse
Species Reactivity:
Rat
Applications:
WB

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Product Overview

Description

Synaptotagmin-6 (SYT6) is a member of the synaptotagmin family, which consists of 13 membrane trafficking proteins that contain a N-terminal transmembrane region, and two cytoplasmic C2 domains. It has been reported that SYT6 plays an important role in Ca2+-dependent exocytosis of secretory vesicles, thus being an essential part of the neurotransmitter release machinery. SYT6 also mediates exocytosis in sperm acrosomal reaction via similar Ca2+-dependent mechanism.

Immunogen

Fusion protein corresponding to amino acids 246-333 (cytoplasmic C2A domain) of mouse Synaptotagmin-6.

Species Reactivity

Rat

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG1, κ

Clone Number

CBP3827

Applications

WB

Application Notes

WB (1.0-10 µg/mL)

Relevant Diseases

Brain Tumors; Alzheimer's Disease; Parkinson's Disease; Neurocutaneous Syndromes

Research Areas

Neuroinflammation; Neurodegeneration

Conjugation

Unconjugated
Product Properties

Form

Liquid

Formulation

PBS, pH 7.2, containing 0.09% sodium azide.

Concentration

0.5 mg/mL

Purification

Affinity Chromatography

Purity

>95%, as determined by Coomassie stained SDS-PAGE.

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the recommended temperature.

Storage

Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody.

Research Use Only

For research use only, not for diagnostic or therapeutic use.
Target

Target

Synaptotagmin-6

Official Name

SYT6

Full Name

Synaptotagmin-6

Alternative Names

SYT6; sytVI; synaptotagmin 6

Gene ID

148281(Human); 54524(Mouse); 60565(Rat)

Uniprot ID

Q5T7P8(Human); Q9R0N8(Mouse); Q62746(Rat)
Publications

Publications (0)

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For Research Use Only. Not For Clinical Use.
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