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Creative Biolabs

Anti-CD55 Monoclonal Antibody (CBP3879)

[CAT#: NAB2012438LS]

Anti-CD55 Monoclonal Antibody [PerCP/Cyanine 5.5 ]

Host Species:
Mouse
Species Reactivity:
Human; African green monkey; Baboon; Cynomolgus
Applications:
FC

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Product Overview

Description

CD55 is a 60-70 kD glycosylphosphatidylinositol (GPI)-anchored single chain glycoprotein also known as decay-accelerating factor (DAF). It is expressed on hematopoietic cells including erythrocytes and many non-hematopoietic cells. CD55 accelerates the dissociation of the components of the C3-convertases to protect cells from inappropriate damage caused by autologous complement. CD55 has been reported to reduce the efficiency of NK cell lysis and induce signal transduction in T cells. CD55 has also been shown to interact with CD97 and bind to Coxsackie and Echovirus.

Species Reactivity

Human; African green monkey; Baboon; Cynomolgus

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG1, κ

Clone Number

CBP3879

Applications

FC

Application Notes

FCM (≤2.0 µg per million cells in 100 µL volume)

Relevant Diseases

Brain Tumors; Alzheimer's Disease; Parkinson's Disease; Neurocutaneous Syndromes

Research Areas

Neuroinflammation; Neurodegeneration

Conjugation

Alexa Fluor 594; Alexa Fluor 488; Alexa Fluor 498; Alexa Fluor 647; Alexa Fluor 700; APC; APC/Cyanine 7; APC/Fire 750; Biotin; Brilliant Violet 421; Brilliant Violet 510; Brilliant Violet 570; Brilliant Violet 570; Brilliant Violet 605; Brilliant Violet 650; Brilliant Violet 711; Brilliant Violet 750; Brilliant Violet 785; FITC; HRP; PE; Pacific Blue; PE/Cyanine 5; PE/Cyanine 7; PerCP; Spark YG 570
Product Properties

Form

Liquid

Formulation

PBS, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA.

Concentration

1.0 mg/mL

Purification

Affinity Chromatography

Purity

>95%, as determined by Coomassie stained SDS-PAGE.

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the recommended temperature.

Storage

The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.

Research Use Only

For research use only, not for diagnostic or therapeutic use.
Target

Target

CD55

Official Name

CD55

Full Name

Decay-accelerating factor

Alternative Names

CD55; CR; CROM; DAF; TC; CD55 molecule (Cromer blood group); CHAPLE

Gene ID

1604 (Human); 13137 (Mouse)

Uniprot ID

P08174 (Human); Q61476 (Mouse)
References

1. Stocks S, et al. 1990. Biochem. J. 268:275.
2. Wright S, et al. 1990. Science 249:1434.
Publications

Publications (0)

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