Product
Mouse Anti-Human VCAM1 Monoclonal Antibody (CBP3973)
[CAT#: NAB2012912LS]
Anti-VCAM1 Monoclonal Antibody
- Host Species:
- Mouse
- Species Reactivity:
- Human
- Applications:
- IF; IP; FC; IHC
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
inquiryProduct Overview
Description
CD106 is a 110 kD single chain type I glycoprotein, which is also known as VCAM-1 and INCAM-110. It is expressed predominantly on activated vascular endothelium but has also been identified on follicular and interfollicular dendritic cells, some macrophages, bone marrow stromal cells, and non-vascular cell populations within joints, kidney, muscle, heart, placenta, and brain. Activated endothelial cells can release soluble forms of CD106 which can be detected in the blood. CD106 binds the integrins CD49d/CD29 (VLA-4) and α4β7 that contribute to leukocyte adhesion, transmigration, and co-stimulation of T cell proliferation.
Immunogen
IL-1β activated human umbilical vein endothelial cells (HUVECs).
Species Reactivity
Human
Clonality
Monoclonal
Host Species
Mouse
Isotype
IgG1, κ
Clone Number
CBP3973
Applications
IF; IP; FC; IHC
Application Notes
IF (1:1000); IP (1:1000); FCM (1:1000); IHC (1:500-1:1000)
Relevant Diseases
Brain Tumors; Alzheimer's Disease; Parkinson's Disease; Neurocutaneous Syndromes
Research Areas
Neuroinflammation; Neurodegeneration
Conjugation
Unconjugated
Product Properties
Form
Liquid
Formulation
PBS, pH 7.2, containing 0.09% sodium azide.
Concentration
1.0 mg/mL
Purification
Affinity Chromatography
Purity
>95%, as determined by Coomassie stained SDS-PAGE.
Shipping
The product is shipped at 4°C. Upon receipt, store it immediately at the recommended temperature.
Storage
Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody.
Research Use Only
For research use only, not for diagnostic or therapeutic use.
Target
Target
VCAM1
Official Name
VCAM1
Full Name
Vascular Cell Adhesion Molecule 1
Alternative Names
Vascular Cell Adhesion Molecule 1; CD106 Antigen; INCAM-100; Vascular Cell Adhesion Protein 1; V-CAM 1; VCAM-1; CD106;
Publications
Publications (0)
Kits
Neural Antibodies
For Research Use Only. Not For Clinical Use.
