Mouse Anti-Human CD11b Monoclonal Antibody (CBP4015)
[CAT#: NAB20121028LS]
Anti-CD11b Monoclonal Antibody
- Host Species:
- Mouse
- Species Reactivity:
- Human
- Applications:
- FC; IP; Block
Certificate of Analysis Lookup
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
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Description
CD11b is a 170 kD glycoprotein, also known as αM integrin, Mac-1α subunit, Mol, CR3 and Ly-40. CD11b is a member of the integrin family and is mainly expressed on granulocytes, monocytes/macrophages, dendritic cells, NK cells, and a subpopulation of T and B cells. CD11b and CD18 (β2 integrin) non-covalently bind to form Mac-1. Mac-1 plays an important role in cell-cell interactions by binding its ligands ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), iC3b and fibrinogen.
Species Reactivity
Human
Clonality
Monoclonal
Host Species
Mouse
Isotype
IgG1, κ
Clone Number
CBP4015
Applications
FC; IP; Block
Application Notes
FCM (≤ 0.5 µg per million cells in 100 µL volume)
Relevant Diseases
Brain Tumors; Alzheimer's Disease; Parkinson's Disease; Neurocutaneous Syndromes
Research Areas
Neuroinflammation; Neurodegeneration
Conjugation
Unconjugated
Product Properties
Form
Liquid
Formulation
0.2 µm filtered in PBS, pH 7.2, containing no preservative.
Concentration
1.0 mg/mL
Purification
Affinity Chromatography
Purity
>95%, as determined by Coomassie stained SDS-PAGE.
Endotoxin Level
Endotoxin level is <0.01 EU/µg of the protein (<0.001 ng/µg of the protein) as determined by the LAL test.
Shipping
The product is shipped at 4°C. Upon receipt, store it immediately at the recommended temperature.
Storage
Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody.
Research Use Only
For research use only, not for diagnostic or therapeutic use.
Target
References
1. Stewart M, et al. 1995. Curr. Opin. Cell Biol. 7:690.
Publications
Publications (0)
Neural Antibodies
For Research Use Only. Not For Clinical Use.
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