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Creative Biolabs
Product

Mouse Anti-Amyloid Precursor Protein Monoclonal Antibody (CBP4050)

[CAT#: NAB2007FY1189]

Mouse Monoclonal (NC4D10) to Amyloid Precursor Protein

Host Species:
Mouse
Species Reactivity:
Human
Applications:
IHC

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Product Overview

Description

Amyloid β (Aβ or Abeta) is a multifunctional peptide of 36-43 amino acids, processed from amyloid precursor protein (APP). Because it is the main component of amyloid plaques in the brain of patients, it is most often associated with Alzheimer's disease. However, it also plays a role in a variety of non-disease activities, including protection against metal-induced reactive oxidants (ROS), modification of cholesterol transport, and potential activity as a transcription factor. It is secreted by platelets into the serum, and its level increases with age.

Immunogen

A synthetic peptide encoding amino acid residues 1-17 of amyloid beta protein.

Species Reactivity

Human

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG1

Clone Number

CBP4050

Applications

IHC

Application Notes

IHC: 40-150 µg
The optimal conditions mµst be determoned by the user.

Relevant Diseases

Alzheimer's Disease

Conjugation

Unconjugated
Product Properties

Form

colorless liquid

Formulation

100 µg (0.5 mg/ml) in 1X PBS, pH 7.4 with 50% Glycerol.

Preservatives

Yes

Purification

Affinity purified

Shipping

Gel Pack

Storage

-20°C

Handling Advice

The antibody solution should be gently mixed before use.
Target

Target

APP

Official Name

APP

Full Name

Amyloid Precursor Protein

Alternative Names

APP; AAA; ABETA; ABPP; AD1; APPI; CTFgamma; CVAP; PN-II; PN2; amyloid beta precursor protein; preA4

Gene ID

351 (Human); 11820 (Mouse); 54226 (Rat)

Uniprot ID

P05067 (Human); P12023 (Mouse); P08592 (Rat)
Publications

Publications (0)

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