Product
Mouse Anti-Human AKR1B1 Monoclonal Antibody (CBP4350)
[CAT#: NAB2101132LS]
Anti-AKR1B1 Monoclonal Antibody
- Host Species:
- Mouse
- Species Reactivity:
- Human
- Applications:
- WB; IHC-P
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
inquiryProduct Overview
Description
Aldo-keto reductase 1 member B1 (AKR1B1) is a member of AKR superfamily and catalyzes the NADPH-dependent reduction of a wide range of carbonyl-containing compounds to their corresponding metabolites. It also plays an important role in glucose metabolism. Elevated expression levels of AKR1B1 correlate with breast cancer, neuroinflammation, and astrocyte proliferation via modulating energy metabolism.
Immunogen
Purified recombinant human AKR1B1 protein.
Species Reactivity
Human
Clonality
Monoclonal
Host Species
Mouse
Isotype
IgG1, κ
Clone Number
CBP4350
Applications
WB; IHC-P
Application Notes
WB ( 0.2 - 5.0 µg/mL); IHC-P (1.0 - 10 µg/mL)
Relevant Diseases
Brain Tumors; Alzheimer's Disease; Parkinson's Disease; Neurocutaneous Syndromes
Research Areas
Neuroinflammation; Neurodegeneration
Conjugation
Unconjugated
Product Properties
Form
Liquid
Formulation
PBS, pH 7.2, containing 0.09% sodium azide.
Concentration
Batch Dependent
Purification
Affinity chromatography
Purity
>95%, as determined by Coomassie stained SDS-PAGE.
Shipping
The product is shipped at 4°C. Upon receipt, store it immediately at the recommended temperature.
Storage
Store at -20°C. Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody.
Handling Advice
Store at -20°C. Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody.
Research Use Only
For research use only, not for diagnostic or therapeutic use.
Target
References
1. Chen X, et al. 2018. Neurochem Res. 43(8):1491-1499.
2. Steinhauser CB, et al. 2016. Biol Reprod. 95(5):108.
3. Wu X, et al. 2017. J Exp Med. 214(4):1065-1079.
4. Han J, et al. 2016. Proc Natl Acad Sci U S A. 113(50):14283-14288.
2. Steinhauser CB, et al. 2016. Biol Reprod. 95(5):108.
3. Wu X, et al. 2017. J Exp Med. 214(4):1065-1079.
4. Han J, et al. 2016. Proc Natl Acad Sci U S A. 113(50):14283-14288.
Publications
Publications (0)
Neural Antibodies
For Research Use Only. Not For Clinical Use.
