Mouse Anti-Gemin 6 Monoclonal Antibody (CBP4378)

[CAT#: NAB2101170LS]

Anti-Gemin 6 Monoclonal Antibody

Host Species:: Mouse

Species Reactivity:: Human; Rat

Applications:: WB

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Product Overview

Description

Gem-associated protein 6 (Gemin 6) is a component of the survival of motor neurons (SMN) macromolecule protein complex, which plays an important role in the assembly and re-structuring of small nucleoproteins and transcriptosomes. The SMN complex localizes to the cytosol and nucleus of eukaryotic cells. Gemin 6 has been shown to form heterodimers with Gemin 7, and together they bind to unrip and sequester the SMN complex in the cytoplasm for small nuclear ribonucleoproteins (snRNP) assembly

Species Reactivity

Human; Rat

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG1, κ

Clone Number

CBP4378

Applications

Application Notes

WB (0.2-10 µg/mL)

Relevant Diseases

Brain Tumors; Alzheimer's Disease; Parkinson's Disease; Neurocutaneous Syndromes

Research Areas

Neuroinflammation; Neurodegeneration

Conjugation

Unconjugated

Product Properties

Form

Liquid

Formulation

PBS, pH 7.2, containing 0.09% sodium azide.

Concentration

0.5 mg/mL

Purification

Affinity chromatography

Purity

>95%, as determined by Coomassie stained SDS-PAGE.

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the recommended temperature.

Storage

Store at -20°C. Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody.

Handling Advice

Store at -20°C. Upon initial thawing, apportion into working aliquots and store at -20°C. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody.