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Creative Biolabs
Product

Mouse Anti-Fibrillarin Monoclonal Antibody (CBP6718)

[CAT#: NAB2007FY1579]

Mouse Monoclonal to Fibrillarin

Host Species:
Mouse
Species Reactivity:
Human; Rat; Mouse; Horse; Dog; Monkey
Applications:
WB; IF; IHC

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Product Overview

Description

Fibrillin is a highly conserved component of mammalian nucleolar small ribonucleoprotein complex, which is involved in the processing of ribosomal RNA during ribosomal biogenesis. The protein runs at ~35kDa on SDS-PAGE and is rich in basic amino acids with a PI of 9.8. Fibrillin was first discovered in humans because of autoantibodies that stain nucleoli in some scleroderma patients with autoimmune diseases (1). It was subsequently discovered that the protein fibrillin is a human homolog of Nop1p (a Saccharomyces cerevisiae nucleolar protein), and the two proteins are 67% identical (2,3).

Immunogen

Recombinant full-length human fibrillin sequence expressed and purified in E. coli.

Species Reactivity

Human; Rat; Mouse; Horse; Dog; Monkey

Clonality

Monoclonal

Host Species

Mouse

Isotype

IgG1

Clone Number

CBP6718

Applications

WB; IF; IHC

Application Notes

WB: 1:2000
IF/ICC and IHC: 1:1000-1:5000
Product Properties

Form

Liquid

Formulation

50% PBS, 50% glycerol

Preservatives

5mM NaN3

Concentration

1 mg/ml

Shipping

Gel Pack

Storage

Store at 4°C for short term, for longer term store at -20°C

Handling Advice

The antibody solution should be gently mixed before use.

Research Use Only

For research use only
Target

Target

Fibrillarin

Official Name

FBL

Full Name

Fibrillarin

Alternative Names

FBL; FIB; FLRN; RNU3IP1; fibrillarin; Nop1

Gene ID

2091 (Human); 14113 (Mouse)

Uniprot ID

P22087 (Human); P35550 (Mouse)
Publications

Publications (0)

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For Research Use Only. Not For Clinical Use.
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