NeuroMab™ Anti-GluN2B/NR2B glutamate receptor, Clone N59/36 (CBP8252)

Product Overview

Immunogen

Fusion protein amino acids 20-271 (extracellular N-terminus) of rat GluN2B/NR2B (also known as Glutamate/N-methyl D-aspartate/NMDA receptor subtype 2B or subunit epsilon 2, N-methyl-Daspartate receptor subunit 3, NMDAR2B, NR3 and Grin2b, accession number Q00960) Mouse: 99% identity (250/252 amino acids identical)
Human: 99% identity (250/252 amino acids identical)
<50% identity with GluN2A/NR2A, GluN2C/NR2C and GluN2D/NR2D

Species Reactivity

Rat; Mouse; Human

Clonality

Monoclonal

Isotype

IgG2b

Clone Number

CBP8252

Applications

WB; IHC; IP; ICC

Application Notes

Does not cross-react with GluN2A/NR2A, GluN2C/NR2C or GluN2D/NR2D (based on KO validation results)

Conjugation

Unconjugated

Product Properties

Research Use Only

For reseaech use only, not for human or dignostic use.

Target

GRIN2B

Official Name

GRIN2B

Full Name

GluN2B/NR2B glutamate receptor

Alternative Names

GRIN2B; GluN2B; MRD6; NMDAR2B; NR2B; hNR3; EIEE27; glutamate ionotropic receptor NMDA type subunit 2B; NR3

Uniprot ID

Q00960

Product Pictures

Fig. 1 Immunoblot against rat brain membranes (RBM) and neuronal lysates from NR2B knockout (KO) and heterozygote (Het) mice.

Fig. 2 Immunoblots on brain membranes prepared from whole rat (RBM) and mouse (MBM) brain, and from human cerebral cortex [HBM(Cx)] and hippocampus [HBM(H)].