NoGeneST™ Anti-APP Aptamer, aAPP aptamer

Name: NoGeneST™ Anti-APP Aptamer, aAPP aptamer
SKU: NRYF-0625-HZ83
Rating: 5 (1 reviews)

[CAT#: NRYF-0625-HZ83]

Aptamer designed to specifically recognize Amyloid Precursor Protein, a central molecule in Alzheimer's disease pathogenesis.

Target:: APP

Datasheet MSDS Request COA

Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number

Inquiry

Product Overview

Species

Human

Relevant Diseases

Alzheimer's Disease

Properties

Size

5 nmol. 10 nmol. 50 nmol

Soluble In

PBS; buffer system with Serum; other

Purity

>90%

Shipping

Room temperature

Storage

Powder Form: Stable for 3 years when stored at -20°C.
In Solvent: Stable for 6 months when aliquoted and stored at -80°C

Research Use Only

For Research Use Only

Target Details

Target

APP

Full Name

Amyloid Beta Precursor Protein

Gene ID

351

Uniprot ID

P05067

Target Overview

Amyloid Beta Precursor Protein (APP) is a single-pass transmembrane protein expressed in many tissues but is concentrated in the synapses of neurons. While its precise physiological functions are still under investigation, it is known to be involved in synaptic plasticity and neural development. APP is most notable for its central role in Alzheimer's disease. It can be sequentially cleaved by secretase enzymes, and one of these processing pathways generates Amyloid-beta (Aβ) peptides. The misfolding and aggregation of these Aβ peptides into amyloid plaques is a primary pathological hallmark of Alzheimer's disease, making APP a critical target for diagnostic and therapeutic research.

Publications