NoGeneST™ Anti-SOD1 Aptamer, aSOD1 aptamer

Name: NoGeneST™ Anti-SOD1 Aptamer, aSOD1 aptamer
SKU: NRYF-0625-HZ100
Rating: 5 (1 reviews)

[CAT#: NRYF-0625-HZ100]

Aptamer designed to specifically recognize Superoxide Dismutase 1, a key antioxidant enzyme implicated in Amyotrophic Lateral Sclerosis (ALS).

Target:: SOD1

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Product Overview

Relevant Diseases

Amyotrophic Lateral Sclerosis

Properties

Size

5 nmol. 10 nmol. 50 nmol

Soluble In

PBS; buffer system with Serum; other

Purity

>90%

Shipping

Room temperature

Storage

Powder Form: Stable for 3 years when stored at -20°C.
In Solvent: Stable for 6 months when aliquoted and stored at -80°C

Research Use Only

For Research Use Only

Target Details

Target

SOD1

Full Name

Superoxide Dismutase [Cu-Zn]

Alternative Names

ALS1; hSod1

Gene ID

6647

Uniprot ID

P00441

Target Overview

Superoxide Dismutase 1 (SOD1) is a vital antioxidant enzyme that is abundant in the cytoplasm of most cells. Its primary physiological role is to protect the cell from oxidative damage by catalyzing the conversion of toxic superoxide radicals into molecular oxygen and hydrogen peroxide. While crucial for cellular health, over 150 different mutations in the SOD1 gene have been identified as a cause of familial Amyotrophic Lateral Sclerosis (ALS). These mutations are thought to confer a toxic gain-of-function, leading to protein misfolding, aggregation, and the progressive death of motor neurons.

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