PRV-CMV-EGFP [Pseudorabies Virus(PRV)]

Pseudorabies virus (PRV) has a double-stranded DNA genome with a genome of approximately 150 kb, which encodes capsid, outer skin, and envelope proteins. The reverse-transcribed anti-synaptic PRV is modified from the vaccine strain Bartha and can be used to analyze the connection structure of the brain center and peripheral neurons. After the virus infects nerve cells, it can replicate in the cell and express the target gene. The offspring virus is transported to the synapse, and then retrogrades the counter-synaptic label of the upstream neuron for further replication and transmission across the synapse.

After years of research, Creative Biolabs has established a stable production platform and can provide pseudorabies virus (PRV) services to promote PRV-based neuron tracking research.

Application field
●Multi-synaptic tracking from the periphery to the center of the brain or from higher to lower brain regions.
●Track the connection between peripheral organs and the central nervous system
●Track the neural network in the disease or injury model.
● Changes in neural networks during neural development.

Virus Vector/Partical

Pseudorabies Virus (PRV)

Neural Tracing

Neural Circuit Mapping

Retrograde

Polysynaptic

Neuron

CMV

Normal Expression

EGFP

Please refer to the protocal.

For research use only.