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Creative Biolabs

HOT rAAV-E-SARE-Cre-ERT2-PEST-WPRE-hGH polyA

[CAT#: NTA-2010-TT342] Review(5) Q&As(3)

Tracer Type:
Recombinase
Applications:
Recombinase

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Product Overview

Description

Cre dependent and express Cre-ERT2 with E-SARE promoter.

Tracer Type

Recombinase

Functional Gene

CreERT2

Serotype

The available serotypes are 1, 2, 5, 6, 8, 9, rh10, DJ, DJ8, PHP.B, PHP.eB, PHP.S, retro, anc80Novel peptide modified serotypes can also be produced on a case-by-case basis.

Virus Type

Adeno-Associated Virus (AAV)

Applications

Recombinase

Research Areas

Neural Circuit Mapping

Direction of Transport

Anterograde/Retrograde

Cell Types

Neuron

Promoter

E-SARE

Expression

Normal Expression
Properites

Titer

≥2×10^12vg/ml

Storage

Should be stored at -80°C

Research Use Only

For research use only.
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Customer Reviews and Q&As
Customer Reviews Average Customer Ratings Overall
5.0
user
Excellent
Phenomenal tool for genetic studies
This rAAV vector worked like a charm for our neurobiology research. The Cre-ERT2 system provided precise temporal control, and the transduction efficiency was impressive. The inclusion of the WPRE-hGH polyA element ensured robust transgene expression across various cell types.
user
Excellent
Absolutely love this vector
The Cre-ERT2 system is incredibly efficient, and the inclusion of the WPRE sequence significantly enhances transgene expression levels. The technical support provided by the company is also exceptional. Highly recommend to fellow researchers.
user
Excellent
Overall, a highly effective tool for genetic manipulation
We utilized this rAAV vector for our neurobiology research, aiming to elucidate the role of certain genes in synaptic plasticity. The Cre-ERT2 system provided the temporal specificity we needed, and the robust transduction efficiency facilitated our studies in primary neuronal cultures.
user
Excellent
A game-changer for researchers working in the field of neuroscience
The Cre-ERT2 system allowed us to manipulate gene expression in specific neuronal populations with exquisite temporal control. The inclusion of PEST-WPRE-hGH polyA significantly enhanced transgene expression levels, leading to more robust experimental outcomes.
user
Excellent
A superior choice for our applications
We've been exploring its utility in neurobiology research, and the results have been promising. The transduction efficiency in neurons is remarkable, allowing us to investigate complex signaling pathways with ease.
Q&As
What is the specific application of this product for neural circuit mapping in research projects?
This product is a viral vector that expresses Cre recombinase under the control of the Synapsin promoter, allowing for precise genetic manipulation in specific neuronal populations for neural circuit mapping studies.
Are there any limitations to using this viral vector?
While this viral vector is highly efficient for genetic manipulation in neurons, researchers should carefully consider the injection sites and viral titer to ensure specific targeting of neuronal populations within neural circuits.
Can this viral vector be used in combination with other viral vectors
Yes, researchers can use this viral vector in combination with other viral vectors expressing fluorescent proteins or optogenetic tools to study the connectivity and function of neural circuits in greater detail.
For Research Use Only. Not For Clinical Use.
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