Creative Biolabs

Rabbit Anti-MKI67 Polyclonal Antibody, Lot. VP20-W817

[CAT#: NAB2007FY1800]

Progenitors

Host Species:
Rabbit
Species Reactivity:
Human
Applications:
IHC; IF

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Description
The antigen KI-67, also known as Ki-67 or MKI67, is a protein encoded by the MKI67 gene in humans (an antigen recognized by the monoclonal antibody Ki-67). Antigen KI-67 is a nuclear protein associated with cell proliferation. Changing the expression level of Ki-67 does not significantly affect cell proliferation in vivo. Ki-67 mutant mice develop normally, and cells lacking Ki-67 proliferate effectively. In addition, it is related to ribosomal RNA transcription. Inactivation of KI-67 antigen leads to inhibition of ribosomal RNA synthesis.
Species Reactivity
Human
Clonality
Polyclonal
Host Species
Rabbit
Isotype
IgG
Applications
IHC; IF
Application Notes
IHC: 1:200-1:500
IF: 0.25-2 µg/ml
Form
Liquid
Formulation
PBS, pH 7.2, 40% glycerol
Preservatives
0.02% Sodium azide
Concentration
0.3 mg/ml
Purification
Affinity purified
Shipping
Gel Pack
Storage
Store at +4°C for short term storage. Long time storage is recommended at -20°C.
Handling Advice
The antibody solution should be gently mixed before use.
Research Use Only
For research use only
Target
Ki67
Official Name
MKI67
Full Name
Antigen KI-67
Alternative Names
MKI67; marker of proliferation Ki-67; KIA; MIB-; MIB-1; PPP1R105
Gene ID
4288(Human); 17345(Mouse); 246042(Rat)
Uniprot ID
P46013(Human); E9PVX6(Mouse)
For Research Use Only. Not For Clinical Use.
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