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Creative Biolabs
Product

NeuroMab™ Rat Anti-IL-10 Monoclonal Antibody (CBP2531)

[CAT#: NAB2007FY883]

Rat Monoclonal [N9D7] to IL-10

Host Species:
Rat
Species Reactivity:
Human
Applications:
ELISA; FC; WB

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Product Overview

Description

Rat anti-human interleukin-10 antibody, recognizes human interleukin-10 (IL-10). IL-10 is an immunomodulatory cytokine expressed by activated CD8 + ve peripheral blood T cells, CD4 + ve T cell clones, B cell lymphomas, activated monocytes and mast cells. According to reports, rat anti-human interleukin-10 antibody, clone JES3-9D7, acts as a neutralizing antibody.

Immunogen

Recombinant human IL-10.
.

Species Reactivity

Human

Clonality

monoclonal

Host Species

Rat

Isotype

IgG1

Clone Number

CBP2531

Applications

ELISA; FC; WB

Application Notes

FC: 1/10-1/50
WB: 1/100

Relevant Diseases

Amyotrophic Lateral Sclerosis; Frontotemporal Dementia

Conjugation

Unconjugated; APC; PE; HRP; Biotin; FITC; Alexa Fluor 488; Alexa Fluor 700; Alexa Fluor 647; Alexa Fluor 750; Alexa Fluor 594; Alexa Fluor 350; Alexa Fluor 1852
Product Properties

Form

Liquid

Formulation

PBS

Preservatives

BSA free

Concentration

1 mg/ml

Purification

Protein G

Endotoxin Level

Low Endotoxin

Shipping

The product is shipped at 4°C. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store at -20°C only. This product should be stored undiluted. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend micr°Centrifugation before use.

Research Use Only

For research use only, not for diagnostic or therapeutic use.
Target

Target

IL-10

Official Name

IL10

Full Name

Interleukin 10

Alternative Names

Interleukin 10

Gene ID

3586(Human)

Uniprot ID

P22301(Human)
References

1. Abrams, J.S. et al. (1992) Strategies of anti-cytokine monoclonal antibody development: immunoassay of IL-10 and IL-5 in clinical samples.
2. Lindmark, E. & Siegbahn, A. (2002) Tissue factor regulation and cytokine expression in monocyte-endothelial cell co-cultures: effects of a statin, an ACE-inhibitor and a low-molecular-weight heparin.
3. Benjamin, J.L. et al. (2011) Randomised, double-blind, placebo-controlled trial of fructo-oligosaccharides in active Crohn's disease.
Publications

Publications (0)

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For Research Use Only. Not For Clinical Use.
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