Creative Biolabs

Recombinant Human A53T Mutant Alpha Synuclein Protein Monomer Protien

[CAT#: NPP2007FY39]

Species:
Human
Tag:
No tag

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Description
Active human recombinant A53T mutant alpha-synuclein protein monomer
Species
Human
Biological Activity
100 µM A53T alpha synuclein protein monomer seeded with 10 µM A53T alpha synuclein protein PFF in 25 µM Thioflavin T (PBS pH 7.4, 100 µl reaction volume) generated a fluorescence intensity of 28 000 Relative Fluorescence Units after incubation at 37°C with shaking at 600 rpm for 56 hours. Fluorescence was measured by excitation at 450 nm and emission at 485 nm on a Molecular Devices Gemini XPS microplate reader.
Expression Host
E. coli
Length
Full Length
Nature
Recombinant
Amino Acids
MDVFMKGLSK AKEGVVAAAE KTKQGVAEAA GKTKEGVLYV GSKTKEGVVH GVTTVAEKTK EQVTNVGGAV VTGVTAVAQK TVEGAGSIAA ATGFVKKDQL GKNEEGAPQE GILEDMPVDP DNEAYEMPSE EGYQDYEPEA
Accession Number
NP_000336.1
Molecule Mass
~14.46 kDa
Tag
No tag
Conjugation
Unconjugated
Relevant Diseases
Alzheimer's Disease; Parkinson's Disease
Applications
WB; SDS-PAGE
Research Areas
Neuroregeneration
Form
Liquid
Formulation
PBS pH7.4
Carrier Protein
Preservative Free
Purification
Ion-exchange Purified
Purity
>95%
Shipping
Dry Ice. Shipping note: Product will be shipped separately from other products purchased in the same order.
Storage
-80°C
Research Use Only
For research use only, not for diagnostic or therapeutic use.
Target
Alpha Synuclein
Official Name
SNCA
Full Name
Alpha-synuclein
Alternative Names
Alpha synuclein protein, Alpha-synuclein oligomer, Alpha synuclein protein oligomer, Alpha-synuclein protein, Non-A beta component of AD amyloid protein, Non-A4 component of amyloid precursor protein, NACP protein, SNCA protein, NACP protein, PARK1 protein, Alpha synuclein oligomers, Alpha Synuclein Protein Oligomers, SYN protein, Parkinson's disease familial 1 Protein; SNCA; NACP; PARK1; PARK4; PD1; synuclein alpha
Gene ID
6622 (Human); 20617 (Mouse)
Uniprot ID
P37840 (Human); P37840 (Mouse)
1. "Genetics Home Reference: SNCA". US National Library of Medicine. (2013).
2. Zhang L., et al. (2008) Brain Res. 1244: 40-52.
3. Alim M.A., et al. (2002) J Biol Chem. 277(3): 2112-2117.
4. Kokhan V.S., Afanasyeva M.A., Van'kin G. (2012) Behav. Brain. Res. 231(1): 226-230.
5. Spillantini M.G., et al. (1997) Nature. 388(6645): 839-840.
Neural Proteins & Peptides
Neural Antibodies
Kits
Neural Vectors
Animal Models
Neural Cell Lines
For Research Use Only. Not For Clinical Use.
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