Creative Biolabs

Recombinant Human IL6 Mature Protein, Active, Low Endotoxin [AA 29 to 212]

[CAT#: NPR2008PZ135]

Species:
Human
Sequence:
29 to 212

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Description
Full length mature protein without the signal peptide.
Species
Human
Biological Activity
It is determined by its ability to stimulate the proliferation of IL-6-dependent mouse 7TD1 cells. The expected ED50 is ≤0.1ng/mL, and the corresponding specific activity is ≥1 x 10e7 units/mg.
Expression Host
Escherichia coli
Length
Full length protein
Nature
Recombinant
Sequence
29 to 212
Amino Acids
PVPPGEDSKD VAAPHRQPLT SSERIDKQIR YILDGISALR KETCNKSNMC ESSKEALAEN NLNLPKMAEK DGCFQSGFNE ETCLVKIITG LLEFEVYLEY LQNRFESSEE QARAVQMSTK VLIQFLQKKA KNLDAITTPD PTTNASLLTK LQAQNQWLQD MTTHLILRSF KEFLQSSLRA LRQM
Accession Number
P05231
Molecule Mass
21 kDa
Applications
FuncS; HPLC; MS; SDS-PAGE
Research Areas
Neurodegeneration
Pathways
Alzheimer's Disease Signaling
Marker
Others
Form
Lyophilized
Purity
>= 95% SDS-PAGE. Purity by HPLC>=95%.
Endotoxin Level
< 1.000 Eu/µg
Shipping
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. For long term storage it is recommended to add a carrier protein on reconstitution (0.1% HSA or BSA).
n/a
This product is an active protein and may elicit a biological response in vivo, handle with caution.
Storage
12 months from date of receipt when stored at -20°C to -80°C as supplied. 1 month when stored at 4°C after reconstituting as directed. 3 months when stored at -20°C to -80°C after reconstituting as directed.

For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Handling Advice
Reconstitute on arrival.
Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-0.5 mg/ml.
Research Use Only
For research use only, not for diagnostic or therapeutic use.
Target
IL-6
Official Name
IL6
Full Name
Interleukin 6 (IL-6)
Alternative Names
IL6; BSF2; HGF; HSF; IFNB2; IL-6; BSF-2; CDF; IFN-beta-2; interleukin 6
Gene ID
3569(Human)
Uniprot ID
P05231(Human)
For Research Use Only. Not For Clinical Use.
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