Creative Biolabs

Rose Bengal [Glutamate uptake inhibitor]

[CAT#: NTA-2101-ZP58]

Potent glutamate uptake inhibitor. Photosensitizing dye.

Biological Activity:
Powerful inhibitor of glutamate absorption (Ki = 19 nM, glutamate is absorbed into isolated synaptic vesicles). Photosensitive dyes. Fluorescein derivatives. Cells are permeable. Causes photothrombotic stroke in vivo.

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Synonyms
Potent glutamate uptake inhibitor. Photosensitizing dye.
Chemical Name
Disodium 2,3,4,5-tetrachloro-6-(2,4,5,7-tetraiodo-6-oxido-3-oxo-3H-xanthen-9-yl)benzoate
Biological Activity
Powerful inhibitor of glutamate absorption (Ki = 19 nM, glutamate is absorbed into isolated synaptic vesicles). Photosensitive dyes. Fluorescein derivatives. Cells are permeable. Causes photothrombotic stroke in vivo.
Modulator Type
Inhibitor
Applications
Ion Indicator
Molecular Weight
1017.64
Form
Form / State: Solid
Excitation
549nm
Emission
570nm
Chemical Formula
C20H2Cl4I4Na2O5
Source
Synthetic
SMILES
O=C(O[Na])c4c(Cl)c(Cl)c(Cl)c(Cl)c4C=2c3cc(I)c(O[Na])c(I)c3OC=1C=2C=C(I)C(=O)C=1I
Solubility
Soluble in water to 75 mM and in DMSO to 25 mM
CAS NO.
CAS Number: 632-69-9
Storage
Store at Room Temperature. The product can be stored for up to 12 months.
Handling Advice
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
For Research Use Only. Not For Clinical Use.
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