Creative Biolabs

Tolcapone [COMT inhibitor]

[CAT#: NMO1120FY068]

COMT inhibitor

Target:
COMT

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Research Areas
Neurodegeneration
Relevant Disease
Parkinson's Disease
Molecular Weight
273.2
Form
Yellow powder
Chemical Formula
C₁₄H₁₁NO₅
Source
Synthetic
SMILES
Cc1ccc(cc1)C(=O)c2cc(O)c(O)c(c2)[N+]([O-])=O
Solubility
Soluble in DMSO (25 mg/ml), or ethanol (25 mg/ml)
CAS NO.
134308-13-7
PubChem Substance ID
4659569
Purity
>98% (HPLC); NMR (conforms)
Storage
-20°C
Shipping
Shipped Ambient
Research Use Only
For research use only
Target
COMT
Official Name
COMT
Full Name
Catechol-O-Methyltransferase
Alternative Names
(3,4-dihydroxy-5-nitrophenyl)-(4-methylphenyl)methanone, Tolcapone, Tasmar, Ro 40-7592
Gene ID
1312 (Human); 12846 (Mouse); 24267 (Rat)
Uniprot ID
P21964 (Human); O88587 (Mouse); P22734 (Rat)
For Research Use Only. Not For Clinical Use.
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