VSV-EnVA-ΔG-eGFP
Combined with AAV-TVA and AAV-VSVG, anterograde monosynaptic
- Tracer Type:
- Anterograde tracing virus
- Applications:
- Neural Tracing
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Lot Number
SPECIFIC INQUIRY
inquiryDescription
Glycoprotein (G) is an important component of VSV anterograde synapse. When G (VSV-ΔG) is removed, it will lose the ability to cross synapses, but it can still express foreign genes in high abundance. Therefore, VSV-ΔG can be used to quickly obtain a complete image of neuron projection distribution, and can also be used for anterograde single synapse tracking.
Creative Biolabs has established a recombinant VSV platform based on our experienced employees and advanced molecular biology technology, and can provide VSV services to promote VSV-based neuron tracking research.
Applications
●Multi-synaptic tracking from the periphery to the center of the brain or from lower to higher brain regions.
●Track the neural network in the disease or injury model.
● Changes in neural networks during neural development.
Tracer Type
Virus Type
Applications
Research Areas
Direction of Transport
Synaptic Restriction
Cell Types
Expression
Fluorophore
Storage
Research Use Only
References
2. Bishnoi, S., Tiwari, R., Gupta, S., Byrareddy, S.N., Nayak, D. Oncotargeting by Vesicular Stomatitis Virus (VSV): Advances in cancer therapy. Viruses. 2018; 10(2): 90.
3. Beier KT, Saunders A, Oldenburg IA, Miyamichi K, Akhtar N, Luo L, Whelan SP, Sabatini B, Cepko CL. Anterograde or retrograde transsynaptic labeling of CNS neurons with vesicular stomatitis virus vectors. Proc Natl Acad Sci U S A. 2011 Sep 13;108(37):15414-9.
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