Creative Biolabs

Z-FA-FMK [Cysteine protease Inhibitor]

[CAT#: MOD2005ZP913]

Irreversible cysteine protease inhibitor. Cell-permeable caspase effector inhibitor.

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Description
Irreversible cysteine ​​protease inhibitor. Cell-permeable inhibitor of caspase effect. Selectively inhibit recombinant effector caspase 2, -3, -6 and -7. Inhibits cathepsins B, L and S, papain and cruzain. Induce apoptosis and necrosis. Shows anti-inflammatory effects in the body.
Chemical Name
Benzyl N-[1-[(4-fluoro-3-oxobutan-2-yl)amino]-1-oxo-3-phenylpropan-2-yl]carbamate
Modulator Type
Inhibitor
Research Areas
Neurodegenerative Diseases
Pathways
Alzheimer's Disease Signaling
Molecular Weight
386.42
Chemical Formula
C21H23N2O4F
Source
Synthetic
SMILES
CC(C(=O)CF)NC(=O)C(CC1=CC=CC=C1)NC(=O)OCC2=CC=CC=C2
Solubility
Soluble in DMSO to 10 mM
CAS NO.
105637-38-5
PubChem Substance ID
122019
Purity
> 95%
Storage
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
Handling Advice
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one week. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
For Research Use Only. Not For Clinical Use.
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