In Vitro Services
In vitro studies in neuroscience play a crucial role in neurological research, especially in drug discovery, toxicity testing, disease modeling, and basic research. Using these research procedures, researchers can manipulate and analyze neural tissues in a controlled environment, screen for potential therapeutic agents, and understand the basic cellular and molecular mechanistic elements of the nervous system. It also avoids some of the ethical issues associated with in vivo research.
Creative Biolabs has been a leading company at the forefront of neuroscience research for over two decades. Our commitment to excellence has driven us to develop high-end in vitro services, revolutionizing the field of neuroscience and paving the way for groundbreaking discoveries.
Service Overview
Cell Culture Models
At Creative Biolabs, we understand the critical role that cell culture models play in neuroscience research. Cultured cells provide an accessible and controllable platform to study various cellular and molecular processes in the nervous system. We offer a wide range of cell culture models, including:
Primary Neuronal Cell Cultures
Neural cells directly from animal brains or human brain tissue, allow researchers to study neurons and glial cells in their native environment, providing valuable insights into cell behavior and function.
Neuronal Cell Lines
Neuronal cell lines and immortalized cell lines from different species, provide a consistent and reproducible source of neural cells and are particularly useful for high-throughput screening and large-scale experiments.
iPSC-derived Neuronal Cells
iPSCs derived from patients with neurodegenerative diseases or healthy donors, which subsequently differentiated into diverse cell types, such as neurons, astrocytes, microglia, and oligodendrocytes. These cells can be manipulated genetically to study disease-related changes.
Neural Organoids
Brain and retinal organoids derived from iPSCs or embryonic stem cells, offer a more complex model of neural development and function and have the potential to model certain aspects of neurodevelopmental disorders and neurodegenerative diseases.
We also offer Customized Cell Culture Model Development service, please contact us for more details.
Cell Viability Assay
Creative Biolabs offers state-of-the-art cell viability assays that enable researchers to screen for any compounds of interest.
By Disease Types
By Cell Types
By utilizing our cell viability and cytotoxicity assays, researchers can identify potential neurotoxic compounds, evaluate the safety of pharmaceutical agents, and gain insights into cell death pathways relevant to neurodegenerative diseases.
Neuronal Plasticity Assay
Neuronal plasticity, or the brain's ability to adapt and reorganize its structure and function, is a fundamental aspect of neuroscience research. Creative Biolabs offers advanced neuronal plasticity assays to investigate synaptic plasticity, long-term potentiation (LTP), and long-term depression (LTD) in cultured neurons.
Neuroinflammation Assay
Neuroinflammation, characterized by the activation of immune responses in the central nervous system, plays a significant role in various neurological disorders, including Alzheimer's disease, multiple sclerosis, and Parkinson's disease. Understanding the intricate mechanisms of neuroinflammation is crucial for developing targeted therapies.
At Creative Biolabs, we offer cutting-edge neuroinflammation assays that enable researchers to study the activation of microglia and astrocytes, the production of pro-inflammatory cytokines, and the effects of anti-inflammatory agents.
Neurochemistry Assay
Neurotransmitters and other neurochemicals are essential for proper neuronal communication and overall brain function. Our neurochemistry assays at Creative Biolabs allow researchers to quantify and analyze various neurochemicals, including neurotransmitters, neuropeptides, and growth factors.
As we continue to expand our capabilities and stay at the cutting edge of technological advancements, Creative Biolabs remains committed to supporting neuroscientists worldwide in their quest to unravel the mysteries of the brain and improve human health.
Please feel free to contact us and discover how we take your neuroscience research to new heights.
Advantages
Specialized Expertise
Team Collaboration
Innovative Strategies
Lower Costs
| Advantages | Descriptions |
|---|---|
| Convenience and Efficiency | Our services provide convenience and efficiency, with specialized equipment and experienced personnel to conduct these complex experiments, thus reducing the excessive workload of researchers. |
| Customization | The service allows for customization of experimental setups to the specific requirements of the individual or organization requesting the service. |
| Advanced Technology | Our advanced in vitro technology supports you in studying individual neurons, synapses or receptors. This allows for more advanced studies that you would not be able to perform in living organisms. |
| Rapid Results | We have the necessary infrastructure and resources to provide bulk services, which can significantly reduce the cost per experiment as well as provide faster turnaround times for results. |
| Data Reliability | Collaborating with us on experiments allows for better control of experimental conditions, and you get more reliable data and stronger conclusions from your research. |
FAQs
Q: What are some common techniques used in in vitro neuroscience research?
A: Common techniques can include patch-clamp electrophysiology, calcium imaging, optogenetics, immunocytochemistry, RNA sequencing, and other molecular biology or biochemistry techniques.
Q: How long can tissues be maintained in in vitro conditions?
A: The duration tissues can be maintained depends on the type of tissue and the specific experimental conditions. Some cultures, such as neuron cultures, can be maintained for several weeks while others like brain slice cultures may last for few days.
Q: What kind of samples can be used for in vitro neuroscience studies?
A: Samples can consist of primary neurons, neuronal cell lines, stem cell-derived neurons, or brain tissue sections.
Q: How are in vitro models for neuroscience developed?
A: These models can be developed using neuronal cells or tissues sourced from humans or animals. Sophisticated techniques such as stem cell technology can also be employed to generate specific types of neurons or brain organoids.
Q: What types of cells are used for in vitro services?
A: Different types of neurons and glial cells are typically used for these services. This includes primary cultures, stem cell-derived neurons, and various immortalized cell lines.
Q: How long does it take to get the results of in vitro testing?
A: The timeframe for results from in vitro testing varies depending on the type and complexity of the test, but it is generally faster than in vivo testing, which can take months or years.
Q: Are in vitro tests costly?
A: The cost of in vitro tests can vary based on the complexity of the experiment, the type and source of cells used, the reagents required, and other factors.
Scientific Resources
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