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Creative Biolabs
Product

NeuroMab™ Anti-Amyloid Beta 1-15 BBB Shuttle Antibody, Clone 2B1

[CAT#: NRZP-1022-ZP3448]

Host Species:
Mouse
Species Reactivity:
Human
Applications:
WB; ELISA; FC; In Vitro; In Vivo

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Product Overview

Description

Brain uptake of therapeutic antibodies is severely limited by their size. To achieve enhanced BBB crossing, Creative Biolabs developed a BBB shuttle antibody platform by utilizing the endogenous macromolecule transportation pathway, known as receptor-mediated transcytosis (RMT). The engineered antibody-based carrier is believed to significantly to increase the macromolecule brain entry to combat CNS diseases.
Notes: The BBB antibody is made-to order and available in a customized format. Please don't hesitate contact us for more details.

Species Reactivity

Human

Clonality

Monoclonal

Host Species

Mouse

Clone Number

2B1

Applications

WB; ELISA; FC; In Vitro; In Vivo
Product Properties

Storage

Store at -20°C. Do not aliquot the antibody.

Research Use Only

For research use only
Target

Target

Amyloid Beta 1-15

Official Name

Amyloid Beta

Full Name

Amyloid Beta

Alternative Names

APP; Aβ; Abeta; Amyloid β
Product Pictures
FCM

Figure 1 illustrates a FACS histogram showing the results of antibody specificity analysis

FCM

Figure 2 illustrates a FACS histogram showing the results of antibody epitope analysis.

FCM

Figure 3 illustrates a FACS histogram showing the results of antibody epitope analysis.

WB

Figure 4 illustrates a photograph of a Western blot showing the results of antibody epitope analysis.

FuncS

Figure 5 is a graph showing the evaluation results of the barrier function control activity of antibodies.

FuncS

Figure 6 is a graph showing the evaluation results of the barrier function control activity of antibodies.

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For Research Use Only. Not For Clinical Use.
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