Product
NeuroMab™ Anti-Tau BBB Shuttle Antibody, Clone 3D6
[CAT#: NRZP-1022-ZP3081]
- Host Species:
- Mouse; Humanized; Chimeric
- Species Reactivity:
- Human
- Applications:
- ELISA; Block; In Vitro; IHC
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
SPECIFIC INQUIRY
inquiryProduct Overview
Description
Brain uptake of therapeutic antibodies is severely limited by their size. To achieve enhanced BBB crossing, Creative Biolabs developed a BBB shuttle antibody platform by utilizing the endogenous macromolecule transportation pathway, known as receptor-mediated transcytosis (RMT). The engineered antibody-based carrier is believed to significantly to increase the macromolecule brain entry to combat CNS diseases.
Notes: The BBB antibody is made-to order and available in a customized format. Please don't hesitate contact us for more details.
Notes: The BBB antibody is made-to order and available in a customized format. Please don't hesitate contact us for more details.
Species Reactivity
Human
Clonality
Monoclonal
Host Species
Mouse; Humanized; Chimeric
Clone Number
3D6
Applications
ELISA; Block; In Vitro; IHC
Product Properties
Storage
Store at -20°C. Do not aliquot the antibody.
Research Use Only
For research use only
Target
Target
Tau
Official Name
MAPT
Full Name
Tau Protein
Alternative Names
MAPT; DDPAC; FTDP-17; MAPTL; MSTD; MTBT1; MTBT2; PPND; PPP1R103; TAU; microtubule associated protein tau; Tau proteins; tau-40
Product Pictures
ELISA
Figure 1 depicts the results of an ELISA screening assay for selected mouse monoclonal anti-tau antibodies.
Block
Figure 2 depicts the results of functional blocking measurements of anti-tau antibodies with selected mouse monoclonal antibodies.
FuncS
Figure 3 depicts disaggregation measurements of selected mouse monoclonal anti-tau antibodies.
FuncS
Figure 4 depicts the results of a tau experiment showing 3D6 and 5G8 immunocapture from human Alzheimer's disease tissue.
FuncS
Figure 5 depicts the results of experiments showing the affinity of humanized 3D6 variants for tau.
Publications
Publications (0)
Kits
Neural Genes
Neural Antibodies
Neural Cell Lines
For Research Use Only. Not For Clinical Use.
