Human AGTRL1 β-Arrestin GPCR Cell Line [CHO-K1]

[CAT#: NCL-7P450]

Species:: Human

Applications:: GPCR Screening

Cell Types:: GPCR Cell

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Product Overview

Description

The β-Arrestin GPCR cell line NCL-7P450 at Creative Biolabs is engineered to co-express PK-labeled GPCR and enzyme receptor (EA) labeled β-Arrestin. Activation of GPCR-PK induces the recruitment of β-Arrestin-EA, forcing the two enzyme fragments to complement each other.

Features

Coupling: Gi/Go
β-Arrestin isoform: β-Arrestin-2
Tag: PK1
Agonist/Ligand: Apelin-13 trifluoroacetate salt

Cell Types

GPCR Cell

Cell Location

β-Arrestin

Applications

GPCR Screening

Assay

GPCR Screening Assay

Readout

β-Arrestin

Assay Characteristics

Coupling: Gi/Go
β-Arrestin isoform: β-Arrestin-2
Tag: PK1
Agonist/Ligand: Apelin-13 trifluoroacetate salt

Species

Human

Properties

Shipping

Dry ice.

Storage

Liquid Nitrogen

Research Use Only

For research use only

Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Target Details

Target

AGTRL1

Official Name

AGTRL1

Alternative Names

AGTRL1; APJ; APJ (apelin) receptor; APJ receptor; APJR; G protein-coupled receptor APJ; G-protein coupled receptor APJ; G-protein coupled receptor HG11; HG11; HG11 orphan receptor; angiotensin II receptor-like 1; angiotensin receptor-like 1; apelin receptor

Publications