Tracer Products
To comprehend the intricate systems of the brain, it is necessary to understand how neurons are connected, to describe the fine structure of neural circuits, and to recognize their functions. Creative Biolabs is committed to the development of tracing tools that can specifically label cell types and visualize conduction directions with controllable directionality to enable precise understanding and research of neural circuit networks.
If you have any specific requests or questions, please contact us right away. Our team of experienced experts are eager to work with you to solve your problems.
Product Overview
Creative Biolabs offers a wide range of neural tracing tools for precise labeling of neural circuits. These tools include traditional tracers (nonviral tracers) and recombinant viral vectors (viral tracers).
- Nonviral tracers are commonly employed to determine neural connections between different brain areas in experimental animals. These substances, which are versatile, extremely sensitive, and capable of selective anterograde and retrograde labeling, have been used to research neural circuits, such as dyes, dextran, proteins, and probes.
- Virus tracers become an effective tool for tracing neural network connections, overcoming the shortcomings of traditional tracers. The most commonly used viral tracing tools for neural circuit mapping are neurotropic viruses, which can infect nerve cells and spread across synapses along neural circuits, making them ideal tools for mapping neural circuits. Herpes simplex virus (HSV), pseudorabies virus (PRV), rabies virus (RV), and vesicular stomatitis virus (VSV) are commonly used neurotropic virus tracing tools. Adeno-associated virus (AAV) is a type of single-stranded DNA replication-deficient virus with a simple structure that has been discovered so far. It has the characteristics of high safety, low immunogenicity, wide range of host cells and long expression time in vivo. A growing number of studies on the neural circuit are using AAV as a tool to trace the neural circuit.
Advantages
- Fast and high efficiency
- Strong background in neural tracing tool
- Hepatotoxicity and strong signal
- Most competitive price
Tracer Type
We have been involved in neuroscience research for many years and have accumulated extensive experience in neural tracing. We are proud to offer a wide range of neural tracer types, including but not limited to:
Intellectual Property
Creative Biolabs is a contract manufacturer that produces tailored viruses and vectors according to client specifications. Importantly, this manufacturing service does not grant Creative Biolabs any intellectual property ownership; all designs and associated intellectual property rights remain exclusively with the customer.
Certain vector components may be subject to third-party intellectual property rights. Creative Biolabs offers publicly available sequence information for these components as a convenience for reference only. The customer assumes full responsibility and liability for the use of these components in their custom vectors. By purchasing vectors containing such components, the customer confirms they have secured all necessary intellectual property licenses, including the right to engage Creative Biolabs for manufacturing.



Low toxicity; Strong tissue penetration ability; Different molecular weights
- Tracer Type:
- Dextan Conjugate
- Applications:
- Neural Tracing


AAV2 Full Capsids
- Tracer Type:
- AAV Capsid
- Applications:
- Control


- Tracer Type:
- Optogenetics
- Applications:
- Optogenetics


- Tracer Type:
- Anterograde tracing virus
- Applications:
- Neural Tracing

Express FLPo recombinase under CAG promoter in a Cre-dependent manner.
- Tracer Type:
- Recombinase

Cre-dependent and express CaMPARI2 under mature neuron specific hSyn promoter.
- Tracer Type:
- Calcium Sensor

Express FLPo recombinase under CAG promoter
- Tracer Type:
- Recombinase

- Tracer Type:
- Apoptosis/Killing

- Tracer Type:
- Helper virus

This AAV expresses oG driven by CAG Promoter in a Cre-dependent manner.
oG (optimized glycoprotein) is a codon-optimized version of a chimeric glycoprotein consisting of the transmembrane/cytoplasmic domain of B19G and the extracellular domain of rabies Pasteur virus strain glycoprotein. It has been reported that oG increases the tracing efficiency for long-distance input neurons up to 20-fold compared to B19G.
- Tracer Type:
- Neuronal circuitry

- Tracer Type:
- Chemogenetics

Retrograde multisynaptic tracing
- Tracer Type:
- Retrograde tracing

- Tracer Type:
- Calcium Sensor

Neurotracing
- Tracer Type:
- Neurotracing

A fascinating tool to detect neuronal circuitry
- Tracer Type:
- Neuronal circuitry

A fascinating tool to detect neuronal circuitry
- Tracer Type:
- Neuronal circuitry

A fascinating tool to detect neuronal circuitry
- Tracer Type:
- Neuronal circuitry

Retrograde multisynaptic tracing
- Tracer Type:
- Retrograde tracing

Neuron silencing
- Tracer Type:
- Chemogenetics

Neuron silencing
- Tracer Type:
- Chemogenetics

Neuron silencing
- Tracer Type:
- Chemogenetics

Neuron silencing
- Tracer Type:
- Chemogenetics

Neuron activation
- Tracer Type:
- Chemogenetics

Neuron activation
- Tracer Type:
- Chemogenetics

Neuron activation
- Tracer Type:
- Chemogenetics


- Tracer Type:
- Helper virus

New generation green 5-HT fluorescent probe
- Tracer Type:
- Neurotransmitter sensor

Brand new red 5-HT fluorescent probe
- Tracer Type:
- Neurotransmitter sensor

Orientation-specific induction of an E-SARE-driven
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