Antibody Discovery Services
Creative Biolabs has long-term devoted to the development and application of monoclonal antibodies for neuroscience research. Equipped with world-leading technology platforms and professional scientific staff, our team of experts can assist you in designing the best study outline customized to meet the requirements of your antibody discovery/development program.
Background of Antibody in Neuroscience Research
In neurobiological research, recombinant antibodies are important reagents to identify the function of proteins of interest. In recent years, the discovery of new potential drug targets and signaling pathways has greatly increased the demand for high-quality neuroscience antibodies. For example, recombinant antibodies against neural targets such as dopamine, beta-amyloid, and serotonin are classical reagents for multiple applications, including Western blotting, ELISA, flow cytometry, immunofluorescence, and immunohistochemistry. What's more, there are different formats of recombinant antibodies to meet the needs of different situations.
Monoclonal Antibody Discovery Service
In the past decades, Creative Biolabs has developed a variety of monoclonal antibodies against neuroscience targets. For example, we have provided our global clients with antibodies targeting various cell types in the nervous systems, such as neurons, astrocytes, oligodendrocytes, and microglia.
It is worth noting that traditional therapeutic antibodies have very limited penetration across the blood-brain barrier so that been banned from the central nervous system. Only about 0.1% of the antibody was able to reach the brain at steady-state concentrations. In this case, Creative Biolabs has developed the novel one-stop single domain antibody (sdAb) discovery service to solve this problem. Compared with traditional antibodies, sdAb presents great advantages due to its small size (12-15 kDa). The small size always results in rapid blood clearance, higher affinity, and great tissue penetration. In addition, sdAbs have a wide theoretical isoelectric point range with pI values between 5 and 10. Highly positively charged pIs enhance the spontaneous permeability of sdAbs across the blood-brain barrier (BBB) to enter the brain and bind intracellular targets.
Applications of Antibodies in Neuroscience
- Facilitate research into proteins involved in the pathogenesis
- Used in biomarker tests for early detection of disease
- For therapeutic antibody drug development
Features of our Antibody Discovery Service
- Full coverage of neurological disease pathways
- Advanced platforms to ensure the best achievement for every single step
- Multiple methods to enhance the success rate
- Reliable lab report with timely update
- Affordable price with the best quality
Creative Biolabs is a leading service provider that focuses on neuroscience research. We are confident in offering novel antibody discovery services for our clients all over the world. If you are interested in our services and products, please do not hesitate to contact us for more details.